Betaine chloride NEW
| Price | $42 | $98 |
| Package | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-04 |
Product Details
| Product Name: Betaine chloride | CAS No.: 590-46-5 |
| Purity: ≥95% | Supply Ability: 10g |
| Release date: 2024/11/04 |
Product Introduction
Bioactivity
| 名称 | Betaine chloride |
| 描述 | Betaine chloride (Betaine hydrochloride) is an acidic form of betaine, a vitamin-like substance observed in grains and other foods; gains the amplification of DNA by decreasing the formation of secondary structure in GC-rich regions. |
| 体外活性 | Exposure to increasing levels of Betaine hydrochloride significantly inhibits HeLa cell proliferation, as demonstrated by the MTT assay (p<0.05). The S phase cell percentage is notably higher in groups exposed to doses below 5 mg/mL compared to those subjected to higher doses, whereas Sub-G1 phase rates exhibit the reverse trend (p<0.05). Concentrations of Betaine hydrochloride above 5.0 mg/mL markedly induce apoptosis in HeLa cells (p<0.01). Superoxide dismutase (SOD) activity in low dose groups slightly exceeds that of the control group (p<0.05). Additionally, there's a noticeable synchrony and correlation in the expression levels of pro-apoptotic genes (Bax, P53, Caspase 3) and the anti-apoptotic gene (Bcl-2). Furthermore, upon inducing apoptosis signals, p53 and cyclin D1 are activated, potentially halting the cell cycle at either the G1/S or S/G2 checkpoints. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | H2O : 43 mg/mL (279.93 mM) |
| 关键字 | Endogenous Metabolite | Betaine Hydrochloride | Betaine chloride | Betaine Chloride | Inhibitor | Betaine | inhibit |
| 相关产品 | Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Formamide | Oleamide | Glycerol | Thymidine | Naringin |
| 相关库 | 经典已知活性库 | 中药单体化合物库 | 生物碱类天然产物库 | EMA 上市药物库 | 药物功能重定位化合物库 | 微生物天然产物库 | 抗癌上市药物库 | 离子通道库 | 古代经典名方目录分子库 | 药食同源库 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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