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Postion:Product Catalog >Biochemical Engineering>Inhibitors>BI-2865
BI-2865
  • BI-2865
  • BI-2865
  • BI-2865

BI-2865 NEW

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Package 10mg 50mg 100mg
Min. Order: 5mg
Supply Ability: 20g
Update Time: 2024-07-13

Product Details

Product Name: BI-2865 CAS No.: 2937327-93-8
Min. Order: 5mg Purity: 98%+ HPLC HNMR
Supply Ability: 20g Release date: 2024/07/13

BI-2865 is a none-covalent pan-KRAS Inhibitor. BI-2865 binds to WT, G12C, G12D, G12V and G13D mutant KRAS with KDs of 6.9, 4.5, 32, 26, 4.3 nM respectively. BI-2865 inhibits the proliferation of G12C, G12D or G12V mutant KRAS expressing BaF3 cells (mean IC50: roughly 140 nM).


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