Bimatoprost NEW
| Price | $30 | $48 | $81 |
| Package | 2mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Bimatoprost | CAS No.: 155206-00-1 |
| Purity: 99.81% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Bimatoprost |
| Description | Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension. |
| In vitro | Bimatoprost is an effective prostaglandin FP receptor agonist, capable of directly inducing a robust and rapid return of calcium ions to baseline levels. It directly activates FP prostaglandin receptors in rats, mice, and humans. |
| In vivo | Bimatoprost displaces [3H] prostaglandin F (2alpha) binding to FP receptors with a Ki of 6.31 μM. It rapidly mobilizes intracellular calcium in 3T3 mouse fibroblasts expressing FP receptors (EC50: 2.2 μM) and human embryonic kidney cells with human FP receptors (EC50: 2.94 μM). Bimatoprost upregulates Cyr61 expression in feline irises and mildly stimulates aqueous humor outflow rate, increasing it by 13% during the day and 14% at night, while reducing tonographic outflow by 26%, thereby lowering intraocular pressure. |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 34 mg/mL (81.8 mM) Ethanol : 77 mg/mL (185.3 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Prostaglandin Receptor | inhibit | Inhibitor | AGN-192024 | Bimatoprost | AGN192024 |
| Inhibitors Related | Angoroside C | Pranoprofen | Tranilast | Rutin | Ozagrel | Ethamsylate | Rebamipide | Evodiamine | Tebufelone | p-Hydroxycinnamic acid |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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