Braco-19 trihydrochloride NEW
| Price | $48 | $113 | $189 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Braco-19 trihydrochloride | CAS No.: 1177798-88-7 |
| Purity: 98.74% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Braco-19 trihydrochloride |
| Description | Braco-19 trihydrochloride (BRACO19 3HCl) is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inhibits HAdV virus replication. |
| In vitro | The IC50 for BRACO-19 trihydrochloride (1.0-10 μM) in UXF1138L cells is 2.5 μM, the IC100 is 5 μM. BRACO-19 trihydrochloride (1 μM) dramatically reduces the expression of nuclear hTERT[3]. BRACO-19 trihydrochloride (0-40 μM) dose-dependently decreases the AdV virus growth in eGFP-transinfected HEK 293 cells. BRACO-19 trihydrochloride (0-150 μM) decreases band intensity in an increasing concentration-dependent manner[4]. |
| In vivo | In nude mice established UXF1138LX Xenografts, BRACO-19 trihydrochloride (2 mg/kg; i.p.) significantly inhibits tumor growth and shows marked single-agent antitumor activity. some animals in the group shows complete regressions (5 of 12 tumors)[3]. |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 19.8 mg/mL (28.2 mM), Sonication is recommended. |
| Keywords | Braco-19 | BRACO19 | BRACO19 Hydrochloride | BRACO-19 Hydrochloride | Braco-19 Trihydrochloride | BRACO 19 Hydrochloride |
| Inhibitors Related | Cyclogalegenin | TMPyP4 tosylate | BIBR 1532 | Zidovudine | Costunolide | RHPS4 | Ceramides Mixture | L-778123 hydrochloride | MST-312 | Adefovir |
| Related Compound Libraries | Bioactive Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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