Bupivacaine hydrochloride monohydrate NEW
| Price | $195 | $483 | $692 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-15 |
Product Details
| Product Name: Bupivacaine hydrochloride monohydrate | CAS No.: 73360-54-0 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2024/11/15 |
Product Introduction
Bioactivity
| 名称 | Bupivacaine hydrochloride monohydrate |
| 描述 | Bupivacaine hydrochloride monohydrate is a potent NMDA receptor inhibitor of sodium, L-calcium, and potassium channels.Bupivacaine hydrochloride monohydrate inhibits SCN5A channels and is commonly used in the study of chronic pain. |
| 体外活性 | Bupivacaine hydrochloride monohydrate inhibits synaptic transmission mediated by NMDA receptors in the spinal dorsal horn, which is an area closely associated with central sensitization[1]. Bupivacaine hydrochloride monohydrate affects the voltage dependence of channel activation and steady-state inactivation by shifting the half-maximal activation/inactivation membrane potential to a slightly more negative membrane potential.In the inactivated state, the SCN5A channel shows slight sensitivity to Bupivacaine hydrochloride monohydrate (IC50=2.18±0.16 μM)[3]. Bupivacaine hydrochloride monohydrate reversibly inhibits SK2 channels in a dose-dependent manner, with an IC50 of 16.5 μM[2]. |
| 存储条件 | Shipping with blue ice. |
| 相关产品 | Minoxidil sulfate | Nisoldipine | Phenytoin sodium | L-Ascorbic acid | Lidocaine | Lidocaine hydrochloride | L-Aspartic aicd sodium | Ethyl cinnamate | 1-Octanol | Indapamide |
| 相关库 | FDA上市及药典收录分子库 | 疼痛相关化合物库 | 神经退行性疾病化合物库 | 经典已知活性库 | 膜蛋白靶向化合物库 | EMA 上市药物库 | 药物功能重定位化合物库 | 抑制剂库 | 已知活性化合物库 | 离子通道库 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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