Product Details
| Product Name:
CD2665 |
CAS No.:
170355-78-9 |
| Purity:
99.67% |
Supply Ability:
10g |
| Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | CD2665 |
| Description | CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM. |
| In vitro | In 3T3 cells, CD2665 (100 nM) abrogates the antiproliferative effects of ATRA, CD271 (adapalene, a RAR-β,γ agonist), and CD2043 (RAR-α,β,γ pan-agonist) returning cell numbers and percent LFCS to control level[1]. |
| In vivo | In mice submitted to 10 months of ethanol consumption, CD2665 (0.6 mg/kg; s.c.) decreases brain RARβ mRNA levels (50% relative to control), without any change in RXR β/γ mRNA levels[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 22.5 mg/mL (46.2 mM)
|
| Keywords | CD2665 | CD-2665 | CD 2665 |
| Inhibitors Related | Isotretinoin | Oxybenzone | MSU-42011 | Tazarotene | Etodolac | KCL-286 | ER 50891 | Acitretin | Tamibarotene | Bexarotene | TTNPB | K-8012 |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Neuronal Differentiation Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$83.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-19 |
United States