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Postion:Product Catalog >API>Antibiotics>Cephalosporins Drugs>Cefmetazole
Cefmetazole
  • Cefmetazole
  • Cefmetazole
  • Cefmetazole
  • Cefmetazole
  • Cefmetazole

Cefmetazole NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-09-01

Product Details

Product Name: Cefmetazole CAS No.: 56796-20-4
EC-No.: 260-384-2 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/09/01

CAS:56796-20-4
MF:C15H17N7O5S3
MW:471.53
EINECS:260-384-2
Product Categories:Pharmaceuticals;Sulfur & Selenium Compounds;Chiral Reagents;Heterocycles;Pharmaceutical intermediate;Medicine intermediate;Intermediates & Fine Chemicals
Mol File:56796-20-4.mol
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Cefmetazole Chemical Properties
Melting point 163-165?C
density 1.4380 (rough estimate)
refractive index 1.7400 (estimate)
storage temp. 2-8°C
solubility Methanol (Slightly, Heated)
pka2.65±0.50(Predicted)
form Solid
color White
Water Solubility Soluble in water
CAS DataBase Reference56796-20-4(CAS DataBase Reference)
Cefmetazole Usage And Synthesis
DescriptionCefmetazole is a cephamycin with a nonaromatic side chain at C-7. In addition to a fairly characteristic second-generation cephalosporin antimicrobial spectrum, it possess fairly significant anti-antiaerobic activity. The ejection of its C-3 side chain leads to alcohol intolerance of the disulfuram type and prolonged clotting times.
Chemical PropertiesWhite Solid
UsesSemi-synthetic antibiotic derived from Cephamycin. Antibacterial.
UsesA broad spectrum second generation cephalosporin antibiotic
DefinitionChEBI: A cephalosporin antibiotic containg an N1-methyltetrazol-5-ylthiomethyl side-chain at C-3 of the parent cephem bicyclic structure.
Antimicrobial activityIt is active against Pr. mirabilis, Pr. vulgaris, Morganella morganii, Yersinia spp.and most anaerobes. S. marcescens is moderately susceptible, but Ps. aeruginosa and E. faecalis are resistant. It is active against Mycobacterium fortuitum and some strains of M. chelonei. It is resistant to a wide range of β-lactamases.
The serum concentration at the end of a 1 g intravenous infusion is around 77 mg/L. Plasma protein binding is 68%. It is principally excreted in the urine with a plasma half-life of c. 1.3 h; 70% is recovered over the first 6 h. In patients whose creatinine clearance is less than 10 mL/min, plasma levels are elevated and the plasma half-life is increased to around 15 h.
Side effects associated with the methylthiotetrazole group at position C-3 have been reported. Uses are similar to those of cefoxitin, but it is not widely available.

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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