Cetrimonium bromide NEW
| Price | $30 | $39 | $55 |
| Package | 50mg | 100mg | 200mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-04 |
Product Details
| Product Name: Cetrimonium bromide | CAS No.: 57-09-0 |
| Purity: ≥95% | Supply Ability: 10g |
| Release date: 2024/11/04 |
Product Introduction
Bioactivity
| 名称 | Cetrimonium bromide |
| 描述 | Cetrimonium bromide (Lauroseptol) is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide. |
| 体外活性 | In a FaDu xenograft tumor model established in SCID mice, intraperitoneal administration of 5 mg/kg Cetrimonium Bromide daily for five consecutive days moderately inhibited tumor growth as compared to the vehicle treatment arm. Additionally, 5 μM of Cetrimonium Bromide effectively prevented tumor formation in FaDu cells within SCID mice. |
| 体内活性 | Cetrimonium Bromide exhibits a dose-dependent and radiation potentiating interaction that inhibits the clonogenic survival of FaDu cells. It induces nuclear pyknosis and bubbling in FaDu cells, consistent with the morphology of apoptotic nuclei, which is not observed in CTAB-treated GM05757 cells. Additionally, it reproducibly suppresses ATPase activity in FaDu cells, achieving approximately 90% inhibition at 50 μM. Cetrimonium Bromide reduces the cell viability in a variety of cell lines including FaDu, C666-1, UTSCC-8A, UTSCC-42A, MRC5, and GM05757 fibroblasts, with respective EC50 values of 2 μM, 3.8 μM, 3.5 μM, 4.2 μM, 11 μM, and 18 μM. It also diminishes the cell viability of A549 lung and MCF7 breast cancer cells with EC50 values of 17 μM and 12 μM, respectively. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 10 mg/mL (27.4 mM), Sonication is recommended. Ethanol : 93 mg/mL (255.2 mM) H2O : 100 mg/mL (274.4 mM) |
| 关键字 | Cetrimonium bromide | Inhibitor | Cetyltrimethylammonium | Hexadecyltrimethylammonium | Cetrimonium | inhibit | Cetrimonium Bromide |
| 相关产品 | Neomycin sulfate | Rifampicin | Ampicillin sodium | Doxycycline (hyclate) | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | EDTA copper(II) disodium salt |
| 相关库 | FDA上市及药典收录分子库 | 经典已知活性库 | 上市药物库 | 抗生素库 | 药物功能重定位化合物库 | NO PAINS 化合物库 | 化妆品成分化合物库 | 已知活性化合物库 | 抗感染化合物库 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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