CGS 15943 NEW
| Price | $39 | $91 | $133 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: CGS 15943 | CAS No.: 104615-18-1 |
| Purity: 99.63% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | CGS 15943 |
| Description | CGS 15943 is an orally bioavailable non-xanthine antagonist of the Adenosine Receptor. In transfected CHO cells, its Ki values for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM, respectively. |
| In vitro | CGS 15943 inhibits the kinase activity of the class IB PI3K isoform p110γ (IC50: 1.1 μM). CGS 15943 shows slight inhibition on p110δ (IC50: 8.47 μM). CGS 15943 (0-20 μM; 24 hours) reduces the phosphorylation of Akt at its residues Ser473 and Thr308 in HLF and Sk-Hep-1 cells. CGS 15943 (0-20 μM; 72 hours) inhibits growth of HLF and SK-Hep-1 cells, as well as HepG2 and PLC-PRF-5 cells[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 12.22 mg/mL (42.77 mM), Sonication is recommended. |
| Keywords | Adenosine Receptor | Phosphoinositide 3-kinase | P1 receptor | CGS15943 | PI3K | inhibit | CGS-15943 | Inhibitor | CGS 15943 |
| Inhibitors Related | Theophylline monohydrate | Myricetin | Erucic acid | Diphylline | Acefylline | Inosine | Theobromine | Isoprenaline hydrochloride | Quercetin | Theophylline | Quercetin Dihydrate | Doxofylline |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Inhibitor Library | Immuno-Oncology Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $197.00/1mg |
VIP3Y
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TargetMol Chemicals Inc.
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2024-11-19 | |
| $2500.00/100mg |
VIP1Y
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TargetMol Chemicals Inc.
|
2024-10-23 | |
| $1.00/1G |
Zhenfei Industrial Co. Ltd.
|
2018-11-21 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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