Chondroitin 4-sulfate NEW

Chinese name: Chondroitin sulfate

English name :Chondroitin 4-sulfate

CAS:24967-93-9

Molecular formula :(C14H19NO14SNa2)n

Molecular weight :499.38

EINECS number: 246-551-2

Density: 1.94

Melting point: 190-194oC

Boiling point: °Cat760mmHg

Appearance: This product is white or yellowish amorphous powder. Tasteless, odorless, hygroscopic, easily soluble in water, insoluble in organic solvents such as ethanol, acetone, ether, etc. Rotation -25°-+35°(c=1, H2O). The characteristic absorption peaks of 725cm-1, 852cm-1 and 930cm-1 were determined by infrared spectroscopy.

Chondroitin sulfate A, also known as 4-chondroitin sulfate, is an acidic mucopolysaccharide composed of (1→4) -O-β-D-glucopyranuronic acid and (1→3) -2-n-acetylamino-2-deoxy-4-o-sulfate-β-d-galactopyranose repeat units. It is one of the components of connective tissue matrix and a cogroup of glycoprotein.

Chondroitin sulfate A changes with age in organisms, from birth to old age, its content gradually decreases, while Chondroitin sulfate C increases.

CSA can enhance the activity of lipase, decompose the triglycerides in chylomicrons into fatty acids, reduce and clarify the chylomicrons in the blood, and also has anticoagulation and antithrombotic effects.

Specific rotation: D-28 to -32°

Storage conditions :2-8°C

Solubility :H2O: 0.1g /mL, slightly hazy, slightly yellow

use

It is used to treat coronary arteriosclerosis, hyperlipidemia, hypercholesterin, angina pectoris, myocardial ischemia, myocardial infarction and other diseases