D-Glucosamine hydrochloride NEW

Price	$6	$2	$0.8
Package	1kg	25kg	100kg

Min. Order:	1kg
Supply Ability:	g-kg-tons, free sample is available
Update Time:	2024-03-29

Product Details

Product Name: D-Glucosamine hydrochloride	CAS No.: 66-84-2
Min. Order: 1kg	Purity: 99%
Supply Ability: g-kg-tons, free sample is available	Release date: 2024/03/29
Lead time: In stock	Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express	Origin: Manufacturer
Name: Sun

1. Product information

Name	D-Glucosamine hydrochloride
Synonym	More Synonyms

Description	Glucosamine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Glucosamine hydrochloride exhibited dose-dependent DPPH antioxidant activity [1]. Short-term (4 h) glucosamine hydrochloride treatment inhibited HIF-1α at the protein level, decreased phosphorylation of p70S6K and S6, translation-related proteins [2]. In the obstructed kidneys and TGF-β1-treated renal cells, glucosamine hydrochloride significantly decreased renal expression of α-smooth muscle actin, collagen I, and fibronectin [3]. In vivo:
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase Research Areas >> Others Natural Products >> Saccharides and Glycosides
References	[1]. Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9. [2]. Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells. Int J Oncol. 2014 May;44(5):1699-706. [3]. Park J, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84.

Description

Glucosamine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Glucosamine hydrochloride exhibited dose-dependent DPPH antioxidant activity [1]. Short-term (4 h) glucosamine hydrochloride treatment inhibited HIF-1α at the protein level, decreased phosphorylation of p70S6K and S6, translation-related proteins [2]. In the obstructed kidneys and TGF-β1-treated renal cells, glucosamine hydrochloride significantly decreased renal expression of α-smooth muscle actin, collagen I, and fibronectin [3]. In vivo:

Related Catalog

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase

Research Areas >> Others

Natural Products >> Saccharides and Glycosides

References

[1]. Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9.

[2]. Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells. Int J Oncol. 2014 May;44(5):1699-706.

[3]. Park J, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84.

Boiling Point	449.9ºC at 760 mmHg
Melting Point	190-194ºC
Molecular Formula	C6H14ClNO5
Molecular Weight	215.632
Flash Point	225.9ºC
Exact Mass	215.056046
PSA	124.01000
Index of Refraction	72 ° (C=1， H2O)

D-Glucosamine hydrochloride MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ6665000

CHEMICAL NAME :
D-Glucose, 2-amino-2-deoxy-, hydrochloride

CAS REGISTRY NUMBER :
66-84-2

LAST UPDATED :
199701

DATA ITEMS CITED :
7

MOLECULAR FORMULA :
C6-H13-N-O5.Cl-H

MOLECULAR WEIGHT :
215.66

WISWESSER LINE NOTATION :
VHYZYQYQYQ1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
15 gm/kg

TOXIC EFFECTS :
Peripheral Nerve and Sensation - sensory change involving peripheral nerve

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Subcutaneous

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
6200 mg/kg

TOXIC EFFECTS :
Peripheral Nerve and Sensation - sensory change involving peripheral nerve

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Intravenous

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
1100 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Parenteral

SPECIES OBSERVED :
Amphibian - frog

DOSE/DURATION :
5 gm/kg

TOXIC EFFECTS :
Peripheral Nerve and Sensation - sensory change involving peripheral nerve

MUTATION DATA

TEST SYSTEM :
Fish - not otherwise specified

DOSE/DURATION :
1000 ppm

REFERENCE :
NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958- Volume(issue)/page/year: 28,176,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T2043 No. of Facilities: 1651 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 16143 (estimated) No. of Female Employees: 13164 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	F: Flammable;Xi: Irritant;Xn: Harmful;
Risk Phrases	R21
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	LZ6665000
HS Code	2932999099

N/A

CAS#:1242172-32-2

D-(+)-Xylose

CAS#:58-86-6

D-(+)-Glucose

CAS#:50-99-7

D-Galactose

CAS#:59-23-4

Detail

Literature: Phytochemistry, , vol. 71, # 11-12 p. 1375 - 1380

Chitosan

CAS#:9012-76-4

D-Glucosamine h...

CAS#:66-84-2

Literature: European Journal of Pharmacology, , vol. 579, # 1-3 p. 74 - 85

Bate-D-Galactos...

CAS#:3006-60-8

D-Glucosamine h...

CAS#:66-84-2

N/A

CAS#:4704-14-7

Literature: Journal of the Chemical Society, , p. 81,85

Precursor 2
CAS#:9012-76-4 Chitosan CAS#:3006-60-8 Bate-D-Galactos...
DownStream 10	Previous 1/3 Next
CAS#:3068-34-6 2-acetamido-2-d... CAS#:3416-24-8 Glucosamine CAS#:41107-82-8 2,5-anhydromannitol CAS#:123-76-2 Levulinic acid

HS Code	2922399090
Summary	2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation.

FEBS J. 281(16) , 3591-608, (2014)

Glucose provides an essential nutrient source that supports glycolysis and the hexosamine biosynthesis pathway (HBP) to maintain tumour cell growth and survival. Here we investigated if short-term glu...

Qualitative and quantitative determination of peptides related to celiac disease in mixtures derived from different methods of simulated gastrointestinal digestion of wheat products.

Anal. Bioanal. Chem 406(19) , 4765-75, (2014)

During wheat digestion, gluten-derived proteolytic resistant peptides are generated, some of them involved in celiac disease. In vitro digestion models able to mimic the peptides generated in the huma...

The dissolution enhancement of piroxicam in its physical mixtures and solid dispersion formulations using gluconolactone and glucosamine hydrochloride as potential carriers.

Pharm. Dev. Technol. 20(1) , 74-83, (2015)

The solid dispersion technique is one of the most effective methods for improving the dissolution rate of poorly water-soluble drugs; however this is reliant on a suitable carrier and solvent being se...

EINECS 200-638-1

MFCD00135831

Glucopyranose, 2-amino-2-deoxy-, hydrochloride, D-

Glucosamine (hydrochloride)

2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.

Or smaller package 1kg/bottle, 10kgs/bottle as request.

Article illustration

3. Shipping

Article illustration

4. Contact information

For more details, pls contact us freely.

Email address : Sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 86 13526505137

Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

Recommended supplier

Product name	Price		Suppliers	Update time
D-Glucosamine hydrochloride	$0.00/1kg	VIP2Y	Hebei Kingfiner Technology Development Co.Ltd	2024-06-11
D-Glucosamine hydrochloride	$10.00/1kg	VIP1Y	Hebei Ganmiao New material Technology Co., LTD	2024-06-07
D-Glucosamine hydrochloride	$30.00/1box	VIP1Y	Shanghai Getian Industrial Co., LTD	2024-06-04
Glucosamine Hydrochloride	$85.00/1kg	VIP1Y	Hebei Zhuanglai Chemical Trading Co.,Ltd	2024-05-21
D-Glucosamine hydrochloride	$0.00/1kg	VIP1Y	Shaanxi TNJONE Pharmaceutical Co., Ltd	2024-04-26
D-Glucosamine hydrochloride	$15.00/1kg	VIP1Y	Ouhuang Engineering Materials (Hubei) Co., Ltd	2024-04-23
D-Glucosamine hydrochloride	$0.00/1kg	VIP1Y	airuikechemical co., ltd.	2024-04-09
D-Glucosamine hydrochloride	$15.00/10kg	VIP1Y	Shandong Juchuang Chemical Co., LTD	2024-03-11
glucosamine Hcl	$20.00/1Box	VIP1Y	zhuzhou dingcheng meihei comestic co.,ltd	2024-01-03
Glucosamine Hydrochloride	$0.00/25kg	VIP1Y	Hangzhou Zelixir Biotech Co., Ltd.	2023-12-04

Henan Fengda Chemical Co., Ltd

1YR

China

Since: 2023-02-10
Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro

INQUIRY

D-Glucosamine hydrochloride NEW

Product Details

Names

D-Glucosamine hydrochloride Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles20

Synonyms

Company Profile Introduction

You may like

Recommended supplier

Henan Fengda Chemical Co., Ltd