D-PANTOTHENIC ACID NEW

• DATA ITEMS CITED :

• 6

• MOLECULAR FORMULA :

• C9-H17-N-O5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Subcutaneous

• SPECIES OBSERVED :

• Rodent - rat

• DOSE/DURATION :

• 3500 mg/kg

• TOXIC EFFECTS :

• Details of toxic effects not reported other than lethal dose value

• REFERENCE :

• JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(1),139,1987

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Intraperitoneal

• SPECIES OBSERVED :

• Rodent - mouse

• DOSE/DURATION :

• 1443 mg/kg

• TOXIC EFFECTS :

• Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity)

• REFERENCE :

• PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 17,32,1983

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Subcutaneous

• SPECIES OBSERVED :

• Rodent - mouse

• DOSE/DURATION :

• 2500 mg/kg

• TOXIC EFFECTS :

• Details of toxic effects not reported other than lethal dose value

• REFERENCE :

• JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(1),139,1987

• TYPE OF TEST :

• LD50 - Lethal dose, 50 percent kill

• ROUTE OF EXPOSURE :

• Unreported

• SPECIES OBSERVED :

• Rodent - mouse

• DOSE/DURATION :

• 2490 mg/kg

• TOXIC EFFECTS :

• Details of toxic effects not reported other than lethal dose value

• REFERENCE :

• BTMNA7 Bitamin. (Nippon Bitamin Gakkai, 4 Ushinomiya-cho, Yoshida, Sakyo-Ku, Kyoto 606, Japan) V.1- 1948- Volume(issue)/page/year: 25,297,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81917 No. of Facilities: 862 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1035 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81917 No. of Facilities: 234 (estimated) No. of Industries: 3 No. of Occupations: 10 No. of Employees: 4854 (estimated) No. of Female Employees: 52 (estimated)