Dauricine NEW

Dauricine was extracted and isolated from the rhizomes of the tetrandrine family. It is a toxic drug. Pharmacological studies have shown that Dauricine has antibacterial, anti-arrhythmia, protective effect on myocardial ischemia, protective effect on cerebral ischemia and anti-tumor effects. The effect is similar to that of quinidine, but has no anticholinergic effect. It can inhibit the transmembrane ion flow of potassium, sodium and calcium, reduce the maximum rise rate and amplitude of action potential phase 0, and prolong the action potential duration of atrial and ventricular muscles. Reduce automaticity and myocardial excitability, slow down heart rate, inhibit myocardial contractility. It has the characteristics of quick onset and slow recovery. Batargyrine is a broad-spectrum antiarrhythmic drug with high efficacy and few side effects. It has been produced and applied in clinic. It is suitable for the treatment of tachyarrhythmia, especially for atrial, borderline and ventricular premature beats. The effect of pre-excitation syndrome with ventricular tachycardia is also good; It has poor effect on atrial flutter and fibrillation.