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Postion:Product Catalog >Pharmaceutical intermediates>Bulk Drug Intermediates>Dimethocaine
Dimethocaine
  • Dimethocaine
  • Dimethocaine
  • Dimethocaine
  • Dimethocaine
  • Dimethocaine

Dimethocaine NEW

Price Get Latest Price
Package 1KG 5KG 25KG
Min. Order: 1KG
Supply Ability: 20 T each week
Update Time: 2023-08-16

Product Details

Product Name: Dimethocaine CAS No.: 94-15-5
EC-No.: 1592732-453-0 Min. Order: 1KG
Purity: 98%~99% Supply Ability: 20 T each week
Release date: 2023/08/16

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Product Name:Dimethocaine
Synonyms:Dimethocaine;NSC 68927;3-Diethylamino-2,2-dimethylpropyl 4-aminobenzoate;4-Aminobenzoic acid 3-(diethylamino)-2,2-dimethylpropyl ester;3-(Diethylamino)-2,2-dimethyl-1-propanol p-aminobenzoate;Larocaine;p-Aminobenzoic acid 3-(diethylamino)-2,2-dimethylpropyl;p-Aminobenzoic acid 3-(diethylamino)-2,2-dimethylpropyl ester
CAS:94-15-5
MF:C16H26N2O2
MW:278.39
EINECS:1592732-453-0
Product Categories:chemical research;medicine grade;pharmaceutical intermediate;94-15-5
Mol File:94-15-5.mol
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Dimethocaine Chemical Properties
Melting point 53.0 to 57.0 °C
Boiling point 421.21°C (rough estimate)
density 1.035
refractive index 1.5290 (estimate)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka10.08±0.25(Predicted)
form Solid
color Pale Orange to Light Orange
Merck 14,3221
InChIInChI=1S/C16H26N2O2/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13/h7-10H,5-6,11-12,17H2,1-4H3
InChIKeyOWQIUQKMMPDHQQ-UHFFFAOYSA-N
SMILESC(OC(=O)C1=CC=C(N)C=C1)C(CN(CC)CC)(C)C
CAS DataBase Reference94-15-5

Safety Information
RTECS UB1575000
MSDS Information

Dimethocaine Usage And Synthesis
DescriptionDimethocaine, also known as DMC or larocaine, is a compound with stimulating effects similar to those of cocaine. It was used in the 1930s as a local anesthetic in dentistry and ophthalmology. Just like cocaine, dimethocaine is addictive due to its stimulation of the reward pathway in the brain. However, dimethocaine is a legal cocaine replacement in some countries and is even listed by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) under the category “synthetic cocaine derivatives”. The structure of dimethocaine, being a 4-aminobenzoic acid ester, resembles that of procaine.
Chemical PropertiesDimethocaine is a yellow chrystalline powder. It is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas.
UsesDimethocaine is a local anesthetic with stimulatory properties that is half the potency of cocaine. It is often abused as a legal substitute for cocaine. The drug is administered intravenously or nasally, because ingestion would lead to rapid hydrolyzation.Its positive effects are euphoria, stimulation, increased talkativeness and mood lift.However, because dimethocaine acts similar as cocaine, it has comparable negative side effects. These side effects include: tachycardia, difficulty with breathing, pain on the chest, vasoconstriction, insomnia, paranoia and anxiety.
DefinitionChEBI: Dimethocaine is a benzoate ester. It is derivate from cocaine, it is not a part of the organic alkaloid mix coming from a coca plant. It is very popular research chemical, mainly used as local anesthetic, but also the stimulant qualities appeared to be shown immediately.
Biological ActivityDimethocaine is a local anesthetic that, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.


Company Profile Introduction

Shandong Huisheng Import & Export Co., Ltd. is located in Jinan city, Shandong Province, is a collection of domestic trade, international trade in one of the diversified services company. Our goal is to provide customers with high quality solutions and one-stop purchasing experience. At present, the company business scope involves five areas: Organic chemical raw materials, inorganic chemical raw materials, fine chemical raw materials, dangerous chemicals and green environmental protection chemical technology project promotion, and we has also established good relations of cooperation with several well-known enterprises and won the strong support of extensive trust from the new and old customers. Products are widely used in automobile, household appliances, office supplies, mobile phone accessories, routers, food, medical and other fields. At present, our business covers 30 countries, and our customers mainly come from Australia, New Zealand, Canada, Germany, France, Poland, South Korea, Russia, Bangladesh, Vietnam, Kazakhstan, India, Ghana, Nigeria, South Africa, Egypt and other more than 30 countries. The company has a sound quality management system and advanced professional equipment, with a positive attitude to meet the changing needs of customers. We take "quality products, quality service, competitive price, timely delivery" as the purpose, looking forward to greater cooperation with overseas customers on the basis of mutual benefit. Our company provides a wide range of products to meet your various needs. Since its inception, the company has always adhered to the "quality first, customer first, reputation first" business policy, wholeheartedly meet the potential needs of our customers. Under the irresistible situation of economic globalization, our company is willing to cooperate sincerely with enterprises around the world to achieve a win-win situation.

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