Product Details
| Product Name:
DJ4 |
CAS No.:
1681020-24-5 |
| Purity:
≥98% |
Supply Ability:
10g |
| Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | DJ4 |
| Description | DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range. |
| In vitro | In cellular functional assays, DJ4 inhibited migration of humanmelanoma, lung, pancreatic and breast cancer cells in a concentration-dependent manner. In live cellimaging over 20h by time-lapse microscopy, DJ4 (2.5 pM ) reduced the migration rate of lung-andbreast-cancer cells by 2.7 and 5.5 times compared to control cells respectively, DJ4 (5 pM) alsoinhibited invasion of MDA-MB-231 breast cancer cells by ~70%. Fluorescent microscopicobservation also revealed that inhibition of activity of these kinases, by DJ4, causes reduction instress fibers which leads to inhibition of cell contractility and migration.[1] |
| Storage | Shipping with blue ice. |
| Solubility Information | DMSO : 5.63 mg/mL (16.05 mM), Sonication is recommended.
|
| Keywords | DJ4 | DJ 4 | DJ-4 |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Acetylcysteine | Kaempferol | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin | Lidocaine hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States