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Postion:Product Catalog >Elubrixin
Elubrixin
  • Elubrixin

Elubrixin NEW

Price $117 $262 $388
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Elubrixin CAS No.: 688763-64-6
Purity: 98.65% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameElubrixin
DescriptionElubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
In vitroElubrixin inhibits neutrophil CD11b upregulation with an IC50 of 260.7 nM and shapes change with an IC50 of 310.5 nM. Elubrixin has an inhibitory effect on neutrophils in a dose-dependent manner[3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 10 mg/mL (21.58 mM)
KeywordsSB656933 | SB 656933 | neutrophil-mediated | Interleukin Related | Inhibitor | inhibit | IL-8 | Elubrixin | CXCR2 | CXCR | CXC chemokine receptors | CD11b | bowel | anti-inflammatory | airway
Inhibitors RelatedInosine pranobex | Apilimod mesylate | Amlexanox | Dexamethasone acetate | L-Arginine | Bergenin | Dexamethasone | α-Terpineol | Diallyl disulfide | Linalool | Nicotinamide N-oxide | Apilimod
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Human Metabolite Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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$1670.00/25mg
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2024-10-28
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TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hills
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