Hot Selling Raw Material Emtricitabine Powder CAS 143491-57-0 Emtricitabine

Introduction

Product Name:Emtricitabine

Synonyms: 4-aMino-5-fluoro-1-[(2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyriMidin-2-one;EMtricitabine (EMtriva)
CAS No. 143491-57-0
EINECS: 604-363-1
Molecular Formula: C8H10FN3O3S
Molecular Weight: 247.25
Specification: 98%
Appearance:White powder

Melting Point :136-140°C

Boiling Point :443.3±55.0 °C(Predicted)

Density :1.82±0.1 g/cm3(Predicted)

Storage:Keep in dark place,Sealed in dry,Room Temperature

Emtricitabine is a New anti-HIV drugs nucleoside reverse transcriptaseinhibitor (NRTI) which has been marketed for the prevention and treatment of HIV infection. It also exhibits clinical activity against the hepatitis B virus (HBV) (not yet approved by FDA).Emtricitabine is a synthetic nucleoside analogue of cytidine. It can be phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate, which competes with the natural substrate deoxycytidine 5'-triphosphate and incorporates into nascent viral DNA, causing early chain termination. Through doing this, it not only lowers the amount of HIV, but also indirectly increases the number of immune system cells (called T cells or CD4+ T-cells).

1. Emtricitabine is used in combination with other antiviral drugs for the treatment of HIV-1 infection in adults. Patients are those who have not been treated with reverse transcriptase inhibitors and those who have been suppressed by reverse transcriptase inhibitor therapy.
2. For the treatment of chronic hepatitis B.
3. The treatment of chronic hepatitis B has a strong antiviral effect, with good safety and tolerance.