ERYTHROSIN B NEW
| Price | $18 |
| Package | 10kg |
| Min. Order: | 1kg |
| Supply Ability: | 5000 |
| Update Time: | 2024-05-10 |
Product Details
| Product Name: ERYTHROSIN B | CAS No.: 16423-68-0 |
| EC-No.: 618-347-7 | Min. Order: 1kg |
| Purity: 99.9 | Supply Ability: 5000 |
| Release date: 2024/05/10 |
| Description | Erythrosin B is an artificial dye widely used in the food and textile industries. Erythrosin B is also a novel photosensitizer which has been used to develop animal models. |
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| Related Catalog | Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others |
| In Vitro | Only the two highest concentrations of Erythrosin B tested (50.0 and 70.0 μg/mL) are significantly different (p<0.05) from the vehicle control group when the Tail Moment and Tail Intensity, which represent the extent of DNA damage, are analyzed. Results show increased micronuclei (MNi) frequencies at six of the seven Erythrosin B concentrations (0.2 to 70.0 μg/mL) when compare to vehicle control group[1]. |
| Cell Assay | The alkaline single-cell gel electrophoresis assay (comet assay) is performed. Briefly, 2×105 HepG2 cells are seeded in a 24-well plate for 24 h. The cells are then treated with Erythrosin B at 0.1, 0.2, 2.0, 10.0, 25.0, 50.0 or 70.0 μg/mL (final concentration) for 4 h; vehicle control (0.7% DMSO) and positive control (doxorubicin0.3 μg/mL) treatments are also performed. The HepG2 cell suspension is mixed with 37°C low-melting point agarose and transferred to normal-melting point agarose-coated slides. One hundred randomly chosen nucleoids are analyzed per treatment, and a total of three independent experiments are performed[1]. |
| References | [1]. Chen W, et al. Establishing an experimental rat model of photodynamically-induced retinal vein occlusion using erythrosin B. Int J Ophthalmol. 2014 Apr 18;7(2):232-8. [2]. Chequer FM, et al. Genotoxic and mutagenic effects of erythrosine B, a xanthene food dye, on HepG2 cells. Food Chem Toxicol. 2012 Oct;50(10):3447-51 |
Company Profile Introduction
Hebei Shengyang Water Conservancy Engineering Co., Ltd. was established in 2018. The group has a construction company, a health product processing company, a chemical raw material production company, and a cosmetics raw material and finished product processing agency. The group has an annual output of 200 million yuan, more than 300 employees, and has 6 modern production lines, testing laboratories, foreign trade business departments, after-sales management departments, and other complete sales systems. The company sells finished products that have undergone third-party testing and certification. We have cooperated with enterprises in multiple countries, and our agents are available in each country. Please inform us of your needs, and the company will fully cooperate,
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China- Since: 2022-08-09
- Address: Haiyue Tiandi, No. 66, Yuhua West Road, Shijiazhuang City, Hebei Province C1503
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