![Flucytosine;5-Fluorocytosine](/ProductImageEN/2024-05/Large/6e2a0347-d630-4969-91c8-82623bec209c.jpg)
Flucytosine;5-Fluorocytosine NEW
Price | Get Latest Price |
Package | 1kg |
Min. Order: | 1kg |
Supply Ability: | 10000kg |
Update Time: | 2024-05-18 |
Product Details
Product Name: Flucytosine;5-Fluorocytosine | CAS No.: 2022-85-7 |
EC-No.: 217-968-7 | Min. Order: 1kg |
Purity: 99% | Supply Ability: 10000kg |
Release date: 2024/05/18 |
Factory Provide Flucytosine CAS 2022-85-7 Strength Vet Materials 99% 5-Fluorocytosine
Introduction
Product Name : Flucytosine;5-Fluorocytosine
Other name:4-amino-5-fluoro-2(1h)-pyrimidinon;4-Amino-5-fluoro-2(1H)-pyrmidinone;5-fluorocystosine
CAS No.: 2022-85-7
MF:C4H4FN3O
MW:129.09
Appearance: White Powder
Melting Point :298-300 °C (dec.) (lit.)
Density :1.3990 (estimate)
Storage :Keep in dark place,Sealed in dry,Room Temperature
Flucytosine has high antibacterial activity against Cryptococcus and Candida, and has certain antibacterial activity against coloring fungi and a few Aspergillus species. The antibacterial effect on other fungi is poor. This product is a bacteriostatic agent and has a bactericidal effect at high concentrations. Because primary or secondary resistance to flucytosine is common, flucytosine is usually used clinically in combination with other antifungal drugs (often combined with amphotericin B).
The drug is a water-soluble nucleotide analog and is well absorbed by oral administration. The product can enter the infected abdominal cavity, joint cavity and aqueous humor, and can penetrate the blood-brain barrier. The drug is widely distributed in liver, kidney, heart, spleen, and lung tissues, and its concentration is greater than or equal to the blood drug concentration in the same period. The drug concentration in inflammatory CSF can reach 50% to 100% of the blood drug concentration in the same period.
Appplication
Flucytosine is used for Candida and cryptococcal infections. The effect of single use is not as good as amphotericin B. It can be combined with amphotericin B to enhance the effect (synergistic effect)
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