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Postion:Product Catalog >Gap19
Gap19
  • Gap19

Gap19 NEW

Price $52 $76 $125
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Gap19 CAS No.: 1507930-57-5
Purity: 98% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameGap19
DescriptionGap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
In vitroHemichannel inhibition is due to the binding of Gap19 to the C-terminus (CT) thereby preventing intramolecular CT-CL interactions.?The peptide inhibited Cx43 hemichannel unitary currents in both HeLa cells exogenously expressing Cx43 and acutely isolated pig ventricular cardiomyocytes.?Treatment with Gap19 prevented metabolic inhibition-enhanced hemichannel openings, protected cardiomyocytes against volume overload and cell death following ischemia/reperfusion in vitro and modestly decreased the infarct size after myocardial ischemia/reperfusion in mice in vivo[2].
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : 5 mM
DMSO : Insoluble
Keywordsmyocardial | cytoplasmic | Cx40/pannexin-1 | inhibit | Gap Junction Protein | C-terminus | Gap 19 | hemichannel | Inhibitor | loop | Gap-19 | Cx43 | channels | connexin | Gap19
Inhibitors RelatedMeclofenamic acid sodium | Carvedilol phosphate hemihydrate | Carbenoxolone disodium
Related Compound LibrariesBioactive Compound Library | Peptide Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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