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Postion:Product Catalog >API>Hormones and the Endocrine System>Pancreatic hormone and blood sugar regulation>Glipizide
Glipizide
  • Glipizide

Glipizide NEW

Price $40
Package 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Glipizide CAS No.: 29094-61-9
Purity: 99.75% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameGlipizide
DescriptionGlipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.
Kinase AssayThe activity of caspase-3, -8 and -9 is assessed using the caspase-3, -8 and -9 colorimetric assay kits, respectively. In brief, 1×106?cells in a 60-mm culture dish are incubated with 10 mM Valproic acid for 24 h. The cells are then washed in PBS and suspended in 5 volumes of lysis buffer provided with the kit. Protein concentrations are determined using the Bradford method. Supernatants containing 50 μg total protein are used to determine caspase-3, -8 and -9 activities. The supernatants are added to each well in 96-well microtiter plates with DEVD-pNA, IETD-pNA or LEHD-pNA as caspase-3, -8 and -9 substrates and the plates are incubated at 37°C for 1 h. The optical density of each well is measured at 405 nm using a microplate reader. The activity of caspase-3, -8 and -9 is expressed in arbitrary absorbance units.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 82 mg/mL (184 mM)
Ethanol : < 1 mg/mL (insoluble or slightly soluble)
Keywordstype 2 diabetes | sulfonylurea class | Glipizide | K ATP | KcsA | Inhibitor | mellitus | Potassium Channel | CP-28720 | inhibit | K-4024 | ATP-sensitive potassium | CP28720 | pancreatic β | K4024
Inhibitors RelatedMinoxidil sulfate | PHYTOL | Daidzein | Fenofibrate | Vismodegib | Halothane | 5-Aminosalicylic Acid | Naringenin | Fisetin | 2,3-Butanediol | Icariin | Indapamide
Related Compound LibrariesAnti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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