Product Details
Product Name:
Imiquimod maleate |
CAS No.:
896106-16-4 |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | Imiquimod maleate |
Description | Imiquimod maleate (R 837 maleate) is a toll-like receptor 7 (TLR7) agonist and immune response modifier with antiviral and antitumor effects. Imiquimod maleate induces psoriatic-like skin lesions in mice and can be used to study various skin malignancies. |
In vivo | In animal models, Imiquimod maleate stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete cytokines and nitric oxide, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α, and inducing proliferation and differentiation of B lymphocytes. [1] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O : 1 mg/mL (2.81 mM.), Sonication is recommended. DMSO : 20 mg/mL (56.12 mM.), Sonication is recommended.
|
Inhibitors Related | Stavudine | Xylitol | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Oxyresveratrol | Paeonol | Naringin | Salicylic acid | Gefitinib |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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