Ivermectin

Ivermectin powder is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum drug resistant parasites.
Ivermectin powder for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae effectively, but for adult worms; For only in intestinal fecal round worms are also effective.
Main Function :
 

1. Ivermectin powder is the derivatives of abamectin. Ivermectin belongs to oral semisynthetic broad-spectrum drug resistant parasites.

2. Ivermectin powder has effect for most of the various life cycle nematodes.

3. Ivermectin powder has effect for the microfilaria of onchocerca volvulus,but it does not has effect for the adult onchocerca volvulus

4. Ivermectin powderhas effect for dung round worms that is only stay in intestinal tract

5. Ivermectin powder has selective inhibition.

6. Ivermectin powder can not go through the blood brain barrier of humanbeings


Application :

In veterinary medicine ivermectin powder is used against many intestinal worms (but not tapeworms), most mites, and some lice. Despite this, it is not effective for eliminating ticks, flies, flukes, or fleas. It is effective against larval heartworms, but not against adult heartworms, though it may shorten their lives. The dose of the medicine must be very accurately measured as it is very toxic in over-dosage.

It is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites. Some dog breeds (especially the Rough Collie, the Smooth Collie, the Shetland Sheepdog, and the Australian Shepherd), though, have a high incidence of a certain mutation within the MDR1 gene (coding for P-glycoprotein); affected animals are particularly sensitive to the toxic effects of ivermectin.

Clinical evidence suggests kittens are susceptible to ivermectin toxicity. A 0.01% ivermectin topical preparation for treating ear mites in cats (Acarexx) is available.

Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray. While this works well in some cases, care must be taken, as several species of reptiles are very sensitive to ivermectin. Use in turtles is particularly contraindicated.