L-2-Hydroxyglutaric acid disodium NEW
| Price | $45 | $83 | $136 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: L-2-Hydroxyglutaric acid disodium | CAS No.: 63512-50-5 |
| Purity: ≥98% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | L-2-Hydroxyglutaric acid disodium |
| Description | L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity(Km and Ki of 2.52 mM and 11.13 mM, respectively). |
| In vitro | L-2-hydroxyglutarate can effectively inhibit 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs), including eleven eleven translocation (TET) enzymes [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : < 1 mg/mL (insoluble） |
| Keywords | 2-Hydroxyglutaric acid disodium | L 2 Hydroxyglutaric acid disodium | modifier | demethylases | methylation | Mitochondrial Metabolism | Histone Demethylase | Inhibitor | renal | cancer | 2-Hydroxyglutaric acid | epigenetic | L-2-Hydroxyglutaric acid | inhibit | histone | L2Hydroxyglutaric acid disodium | L-2-Hydroxyglutaric acid disodium |
| Inhibitors Related | Imeglimin hydrochloride | Rotenone | Boscalid | D-Histidine |
| Related Compound Libraries | Histone Modification Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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