Liraglutide NEW
Price | $50 | $30 |
Package | 1kg | 100kg |
Min. Order: | 1kg |
Supply Ability: | 50tons |
Update Time: | 2024-01-08 |
Product Details
Product Name: Liraglutide | Min. Order: 1kg |
Purity: 99.60% | Supply Ability: 50tons |
Release date: 2024/01/08 |
Wickr ME : bellerea
whatsapp: +8613323046748
Email: nicoy@whby-chem.com
Synonyms:Liraglutide Acetate,Liraglutidum,Liraglutidum Powder
CAS:204656-20-2
MF:C172H265N43O51
MW:3751.202g/mol
EINECS:810-818-7
Appearance:White lyophilized powder
Purity:99%
Reconstitution:Required
Storage:After reconstitution store at 2°C - 8°C
Liraglutide (NN2211) is a long-acting gluca on-like peptide-1 receptor agonist, binding to the same receptors as does the endogenous metabolic hormone GLP-1 that stimulates insuli secretion. Marketed under the brand name Victoza, it is an injectable drug developed by Novo Nordisk for the treatment of type 2 diabetes. In 2015, Novo Nordisk began marketing it in the U.S. under the brand name as a treatment for obesity in adults with at least one weight-related comorbid condition.
Liraglutide was approved for treatment of type 2 diabetes by the European Medicines Agency (EMA) on July 3, 2009, and by the U.S. Food and Drug Administration (FDA) on January 25, 2010. More recently, Liraglutide was approved by the FDA on December 23, 2014 for treatment for obesity in adults with some related comorbidity.
In common to various degrees with other GLP-1 receptor agonists,liraglutide has advantages over more traditional therapies for type 2 diabetes:
1. Liraglutide acts in a glucose-dependent manner, meaning Liraglutide will stimulate insu.lin secretion only when blood glucose levels are higher than normal, preventing "overshoot".Consequently, Liraglutide shows negligible risk of hypoglycemia.
2. Liraglutide has the potential for inhibiting apoptosis and stimulating regeneration of beta cells (seen in animal studies).
3. Liraglutide decreases appetite and inhibits body weight gain,as shown in a head-to-head study versus glimepiride.
4. Liraglutide lowers blood triglyceride levels.
Appearance | White powder. |
Purity | 99%min |
Single Impurity (HPLC) | 1.0%max |
Amino Acid Composition | ±10% of theoretical |
Peptide Content (N%) | ≥80.0% |
Water Content(Karl Fischer) | ≤6.0% |
Acetate Content (HPIC) | ≤15.0% |
MS(ESI) | Consistent |
Mass Balance | 95.0~105.0% |
Specific Rotation (20/D) | -65.0~-75.0°(c=0.5 1%HAc) |
Solubility | H 2 O:40 mg / mL |
Storage condition | -20ºC |
Shelf life | 2 years |
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Wickr ME : bellerea
whatsapp: +8613323046748
Email: nicoy@whby-chem.com
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