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Postion:Product Catalog >LM11A-31 dihydrochloride
LM11A-31 dihydrochloride
  • LM11A-31 dihydrochloride

LM11A-31 dihydrochloride NEW

Price $38 $82 $121
Package 10mg 25mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-14

Product Details

Product Name: LM11A-31 dihydrochloride CAS No.: 1243259-19-9
Purity: ≥98% Supply Ability: 10g
Release date: 2024/11/14

Product Introduction

Bioactivity

名称LM11A-31 dihydrochloride
描述LM11A-31 dihydrochloride is a water-soluble, non-peptide with high blood-brain barrier permeability.LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist.
体内活性LM11A-31 (orally; 50 or 75 mg/kg) administered for 3 months starting at 6-8 months of age prevents and/or reverses atrophy of basal forebrain cholinergic neurites and cortical dystrophic neurites in mid-stage male APPL/S mice[2].?LM11A-31 (oral gavage;?50 mg kg/day for 4 weeks) significantly mitigates proNGF accumulation and preserves BRB integrity[1].
存储条件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度H2O : 125 mg/mL (395.23 mM), Sonication is recommended.
关键字cholinergic | proNGF | Inhibitor | inhibit | LM11A-31 | growth | dystrophy | disease | p75 | Neurotensin Receptor | LM-11A-31 dihydrochloride | nerve | neurite | receptor | barrier | neurotrophin | factor | Ligand | LM11A 31 dihydrochloride | blood-brain | LM11A31 dihydrochloride | Alzheimer's | p75NTR | LM11A-31 Dihydrochloride
相关库经典已知活性库 | 药物功能重定位化合物库 | 血脑屏障通透化合物库 | 抑制剂库 | NO PAINS 化合物库 | 口服活性化合物库 | 临床期小分子药物库 | 已知活性化合物库

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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