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Postion:Product Catalog >Chemical Reagents>Organic reagents>Guanidine salt>m-Chlorophenylbiguanide hydrochloride
m-Chlorophenylbiguanide hydrochloride
  • m-Chlorophenylbiguanide hydrochloride

m-Chlorophenylbiguanide hydrochloride NEW

Price $35 $55
Package 200mg 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: m-Chlorophenylbiguanide hydrochloride CAS No.: 2113-05-5
Purity: 99.87% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Namem-Chlorophenylbiguanide hydrochloride
Descriptionm-Chlorophenylbiguanide hydrochloride is a 5-HT3 receptor agonist. m-Chlorophenylbiguanide hydrochloride selectively binds 5-HT3(Ki: 0.002 µM) over 5-HT1A(Ki: 10 µM) and 5-HT2(Ki: 10 µM) receptors but also binds to high and low affinity sites on the dopamine transporter(DAT; IC50s: 0.4 and 34.8 µM, respectively, in rat caudate putamen synaptosomal membranes).
In vivom-Chlorophenylbiguanide hydrochloride induces depolarization of isolated rat vagus nerve and stimulates inositol phosphate formation in rat frontocingulate cortical slices (EC50s = 0.05 and 4.2 μM, respectively).m-Chlorophenylbiguanide hydrochloride induces bradycardia, an effect that can be reversed by the 5-HT3 receptor antagonist ondansetron, in anaesthetized cats (ED50 = 20.3 nmol/kg)[1].
Storagestore under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 60 mg/mL (241.83 mM)
H2O : < 20 mg/mL (80.61 mM)
KeywordsmChlorophenylbiguanide hydrochloride | m-Chlorophenylbiguanide Hydrochloride | m Chlorophenylbiguanide hydrochloride
Inhibitors RelatedAlverine citrate | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Trazodone hydrochloride
Related Compound LibrariesBioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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