MAO-B-IN-22 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: MAO-B-IN-22 | CAS No.: 2902600-76-2 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | MAO-B-IN-22 |
| Description | MAO-B-IN-22 (compound 6h) is a potent MAO-B inhibitor with an IC50 value of 0.014 μM, exhibiting significant antioxidant activity, effective metal-chelating properties, adequate BBB permeability, and notable neuroprotective effects [1]. |
| In vitro | MAO-B-IN-22 (compound 6h) demonstrated dose-dependent protection against hydrogen peroxide-induced oxidative damage, enhancing cell viability at concentrations of 2.5 to 50 μM over 24 hours [1]. At lower concentrations of 0.5 to 10 μM, it reduced LPS-induced NO production in a dose-dependent manner, indicating anti-neuroinflammatory activity [1]. |
| In vivo | MAO-B-IN-22 (compound 6h) (53.5 mg/kg, administered via oral gavage once daily for three weeks) can alleviate motor impairments in mice by inhibiting MAO-B, increasing dopaminergic neurotransmitter levels, and reducing oxidative damage caused by reactive oxygen species (ROS), potentially mitigating motor dysfunction induced by MPTP and improving symptoms of Parkinson's disease (PD) in vivo [1]. |
| Storage | Shipping with blue ice. |
| Inhibitors Related | Norharmane | J-147 | Azure B | Iproniazid Phosphate | Paeonol | Isatin | Methylene Blue | Pargyline hydrochloride | Methylene Blue trihydrate | Phenelzine sulfate | Pargyline | Bifemelane hydrochloride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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