Maraviroc NEW
| Price | $50 |
| Package | 25KG |
| Min. Order: | 25KG |
| Supply Ability: | 200ton |
| Update Time: | 2023-07-27 |
Product Details
| Product Name: Maraviroc | CAS No.: 376348-65-1 |
| EC-No.: 609-456-0 | Min. Order: 25KG |
| Purity: 98 | Supply Ability: 200ton |
| Release date: 2023/07/27 |
| Product Name: | Maraviroc |
| Synonyms: | Maraviroc;Maraviroc(UK427857);4,4-Difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide;UK-427857; CELSENTRI;CS-49;maroviroc;4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxamide;Maraviroc(Selzentry) |
| CAS: | 376348-65-1 |
| MF: | C29H41F2N5O |
| MW: | 513.68 |
| EINECS: | 609-456-0 |
| Product Categories: | UK-427857, Celsentri;Other APIs;Anti-AIDS;Chiral Reagents;Inhibitors;Pfizer compounds;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 376348-65-1.mol |
| Melting point | 79-81°C |
| density | 1.29±0.1 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: >30mg/mL |
| pka | 7.3(at 25℃) |
| form | white powder |
| color | White |
| optical activity | [α]-15/D |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| InChI | InChI=1/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25-,26-/s3 |
| InChIKey | GSNHKUDZZFZSJB-RWJISDSDNA-N |
| SMILES | C(N1[C@@H]2CC[C@H]1C[C@H](N1C(=NN=C1C(C)C)C)C2)C[C@@H](C1C=CC=CC=1)NC(C1CCC(F)(F)CC1)=O |&1:2,5,7,19,r| |
| CAS DataBase Reference | 376348-65-1(CAS DataBase Reference) |
| Hazard Codes | Xn |
| Risk Statements | 48/22 |
| Safety Statements | 22-36 |
| WGK Germany | 1 |
| Hazardous Substances Data | 376348-65-1(Hazardous Substances Data) |
| Chemical Properties | Brown Solid |
| Originator | Pfizer (US) |
| Uses | Maraviroc is a potent, non-competitive CCR5 receptor antagonist; inhibits binding of HIV viral coat protein gp120. Antiviral. |
| Uses | Potent, non-competitive CCR5 receptor antagonist; inhibits binding of HIV viral coat protein gp120. Antiviral |
| Uses | Maraviroc is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM, respectively |
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Japan
- Since: 2017-12-08
- Address: Building A, Enjoy city, Zhongshan East Road, Shijiazhuang city, Hebei province
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