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Postion:Product Catalog >Chemical pesticides>Germicide>Mefentrifluconazole
Mefentrifluconazole
  • Mefentrifluconazole

Mefentrifluconazole NEW

Price $84 $198 $328
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-28

Product Details

Product Name: Mefentrifluconazole CAS No.: 1417782-03-6
Purity: 99.88% Supply Ability: 10g
Release date: 2025/04/28

Product Introduction

Bioactivity

NameMefentrifluconazole
DescriptionMefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM). Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrum antifungal agent.
In vivoIn the acute and repeat dose toxicity studies performed with Mefentrifluconazole.?A single-dose administration to rats the LD50 is >2000?mg/kg bwt by the oral route, >5000?mg/kg bwt by the dermal route, and >5.314?mg/L by inhalation as a dust aerosol.?Mefentrifluconazole is not a skin or an eye irritant, nor is it a phototoxicant in vitro.In the acute neurotoxicity study in rats, Mefentrifluconazole (oral administration;?2000?mg/kg bwt;?single dose) gives rise to reduce body weight gain and transient neurobehavioral effects only on the day of treatment (unsteady gait, reduced motor activity, reduces grip strength of the forelimbs and increased distance between the hind limbs in the landing foot-splay test).In the repeated-dose toxicity studies, the liver is the target organ in each of the three species investigated.?At higher dose levels in the rat (oral diets;?383/334 mg/kg/bwt/d (4000 ppm)) and the C57BL/6JRj mouse (61 mg/kg bwt/d (300 ppm)), reduces body weight gain and food consumption, alters clinical chemistry parameters, increases liver weight and is accompanied by liver cell hypertrophy, and/or liver cell necrosis.?At low doses, increases liver weight is not associated with any histopathological alterations and is considered to be an adaptive change to treatment.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (251.40 mM), Sonication is recommended.
Keywordsnecrosis | Mefentrifluconazole | liver | irritant | Inhibitor | inhibit | hypertrophy | Fungal | derivative | Cytochrome P450 | CYPs | CYP51A | cell | azole | aromatase | antifungal
Inhibitors RelatedDehydroacetic acid sodium | Chlorobutanol hemihydrate | 2-Butyl-1,2-benzisothiazolin-3-one | Tebuconazole | Potassium gluconate | Chitosan (MW 150000) | Methyl 2-amino-5-bromobenzoate | Paclobutrazol | Lauryl betaine | Geraniol | Naringin | Naringenin
Related Compound LibrariesBioactive Compound Library | Anti-Fungal Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Orally Active Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Metabolism Disease Compound Library | Anti-Infection Compound Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$84.00/1mg
VIP3Y
TargetMol Chemicals Inc.
2025-04-28
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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