Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Analytical Chemistry>Standard>Standard Substance>Mirtazapine
Mirtazapine
  • Mirtazapine
  • Mirtazapine
  • Mirtazapine
  • Mirtazapine
  • Mirtazapine

Mirtazapine NEW

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 10000kg
Update Time: 2024-05-21

Product Details

Product Name: Mirtazapine CAS No.: 61337-67-5
EC-No.: 641-354-1 Min. Order: 1kg
Purity: 99% Supply Ability: 10000kg
Release date: 2024/05/21

Factory Provide Bulk Mirtazapine Powder CAS 61337-67-5


Article illustration

Introduction

Product Name :Mirtazapine

Other name:1,2,3,4,10,14B-HEXAHYDRO-2-METHYLPYRAZINO[2,1-A]PYRIDO[2,3-C][2]BENZAZEPINE

CAS No.: 61337-67-5

MF: C17H19N3

Article illustration

MW:265.35

Appearance: White Powder

Melting Point :114-116°C

Storage :Keep in dark place,Sealed in dry,Room Temperature


Mirtazapine is an atypical antidepressant with noradrenergic and specific serotonergic activity. It blocks the α2 adrenergic auto- and heteroreceptors (enhancing serotonin release), and selectively antagonizes the 5-HT2 serotonin receptors in the central and peripheral nervous system. It also enhances serotonin neurotransmission at the 5-HT1 receptor and blocks the histaminergic (H1) and muscarinic receptors. Mirtazapine is not a serotonin or norepinephrine reuptake inhibitor but may increase serotonin and norepinephrine by other mechanisms of action.
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA) introduced by Organon International in the United States in 1996, and is used primarily in the treatment of depression. It is also commonly used as an anxiolytic, hypnotic, antiemetic and appetite stimulant. In structure, mirtazapine can also be classified as a tetracyclic antidepressant (TeCA) and is the 6-aza analogue of mianserin. It is also racemic-occurs as a combination of both (R)-(?)- and (S)-(+)-stereoisomers, both of which are active.

Mirtazapine is a potent tetracyclic antidepressant.Target: 5-HT ReceptorMirtazapine, the novel antidepressant, has a dual mode of action. It is a noradrenergic and specific serotonergic antidepressant (NaSSA) that acts by antagonizing the adrenergic alpha2-autoreceptors and alpha2-heteroreceptors as well as by blocking 5-HT2 and 5-HT3 receptors.Mirtazapine appears to have a substantial ameliorating effect on hot flushes and perspiration bouts. It is postulated that the 5-HT(2A) blocking properties of mirtazapine is accounted in the symptomatic relief of hot flushes. After 4-24 weeks of treatment, mirtazapine induced downregulation of platelet alpha(2A)-adrenoceptors (up to 34%) and Galphai proteins (up to 28%), and the upregulation of GRK 2 (up to 30%). Treatment with mirtazapine reversed this abnormality and induced downregulation of alpha(2A)-adrenoceptor/Galphai complex.


Appplication

Mainly used to treat all kinds of depression. It is effective for symptoms such as anhedonia, psychomotor depression, poor sleep (early awakening), and weight loss. It can also be used for other symptoms such as loss of interest in things, suicidal thoughts, and mood swings (good morning, bad night). This medicine takes effect after 1-2 weeks of administration.

Mirtazapine is used to treat depression. Mirtazapine is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain to maintain mental balance.

Article illustration



Company Profile Introduction

Shaanxi TNJONE Pharmaceutical Co., Ltd supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Shaanxi TNJONE Pharmaceutical Co., Ltd.'s marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$90.00/1kg
VIP2Y
Zibo Hangyu Biotechnology Development Co., Ltd
2023-10-31
$100.00/1g
Shijiazhuang Gantuo Biotechnology Co., Ltd
2023-03-09
$50.00/1KG
Jiangsu Monade Biological Technology Co., Ltd.
2021-10-21
$1.00/1KG
Wuhan Dujiang Industrial Co., Ltd.
2021-10-20
$15.00/1KG
Zhuozhou Wenxi import and Export Co., Ltd
2021-07-09
$1.00/1KG
VIP4Y
WUHAN FORTUNA CHEMICAL CO., LTD
2021-06-21
$1.00/1kg
VIP7Y
Career Henan Chemical Co
2018-12-25

Shaanxi TNJONE Pharmaceutical Co., Ltd

1YR ChinaChina
  • Since: 2019-05-23
  • Address: No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New C
INQUIRY