Monensin sodium salt NEW
Price | $42 | $58 |
Package | 100mg | 200mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Monensin sodium salt | CAS No.: 22373-78-0 |
Purity: 98.9% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Monensin sodium salt |
Description | Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretion |
In vitro | Monensin sodium salt (Coban), isolated from Streptomyces cinnamonensis, is a well-known representative of naturally polyether ionophore antibiotics. Monensin is an ionophore related to the crown ethers with a preference to form complexes with monovalent cations such as: Li+, Na+, K+, Rb+, Ag+, and TI+. [1] Monensin A is able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport, and exhibits antibiotic, antimalarial, and other biological activities. [2] The antibacterial properties of monensin and its derivatives are a result of their ability to transport metal cations through cellular and subcellular membranes. [3] |
In vivo | LD50: Mice 335 mg/kg (i.g.) [4]; Rats 36.5 mg/kg (i.g.); Chickens 185 mg/kg (i.g.). [5] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | Ethanol : 69.3 mg/mL (100 mM) DMSO : < 1 mg/mL (insoluble) |
Keywords | Sodium/hydrogen Exchanger | Antibiotic | Monensin | Monensin sodium salt | Monensin sodium | Monensin A sodium | inhibit | Monensin A | Bacterial | Inhibitor | Na+/H+ Exchanger (NHE) | Sodium-hydrogen Exchanger |
Related Compound Libraries | Anti-Tumor Natural Product Library | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Natural Product Library | Antiparasitic Natural Product Library | Microbial Natural Product Library | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Ion Channel Targeted Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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