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Postion:Product Catalog >MONNA
MONNA
  • MONNA

MONNA NEW

Price $33 $89 $128
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: MONNA CAS No.: 1572936-83-4
Purity: 98.29% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameMONNA
DescriptionMONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.
In vitroThe TMEM16A-specific inhibitor, MONNA, hyperpolarised the membrane potential in U46619.?MONNA, T16Ainh -A01, and Ani9 attenuated 5-HT/U46619-induced contractions.?MONNA and T16Ainh -A01 also increased coronary flow in Langendorff perfused rat heart preparations.?TMEM16A mRNA was increased in coronary artery smooth muscle cells from SHRs, and U46619 and 5-HT were more potent in arteries from SHRs than in those from normal Wistar rats.?MONNA diminished this increased sensitivity to U46619 and 5-HT[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 25 mg/mL (73.89 mM)
KeywordsMONNA | Cl-Channels | inhibit | Inhibitor | Chloride Channel
Inhibitors RelatedSelamectin | D-Alanine | Niflumic acid | Urethane | Flufenamic acid | Lubiprostone | Halothane | Betaine chloride | Fenamic acid | Meticrane | Adjudin | Guanidinoethyl sulfonate
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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