MUSCIMOL HYDRATE

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MUSCIMOL HYDRATE Basic information

Product Name: MUSCIMOL HYDRATE

Synonyms: MUSCIMOL HYDRATE;5-(aminomethyl)-3(2h)-isoxazolonmonohydrobromide;5-(aminomethyl)-3-isoxazololmonohydrobromide;5-(aminomethyl)-3-isoxazolomonohydrobromide;5-(AMMOMETHYL)-3-ISOXAZOLOL H20;5-(AMINOMETHYL)-3-HYDROXYISOXAZOL HYDRATE;Nsc304080;MUSCIMOL HBR

CAS: 18174-72-6

MF: C4H6N2O2.BrH

MW: 195.01

EINECS:

Product Categories: Enzyme substrates;Neurochemicals

Mol File: 18174-72-6.mol

MUSCIMOL HYDRATE Structure

MUSCIMOL HYDRATE Chemical Properties

Melting point 172 °C

storage temp. 2-8°C

solubility ethanol: 1 mg/mL

form powder

color off-white

Stability: Store in freezer at -20°C

Safety Information

Hazard Codes T

Risk Statements 25

Safety Statements 22-36/37/39-45

RIDADR UN 1544 6.1/PG 2

WGK Germany 3

RTECS NY3345000

MSDS Information

MUSCIMOL HYDRATE Usage And Synthesis

Description Muscimol HBr (18174-72-6) is a GABA-A receptor agonist.

Chemical Properties Tan Solid

Uses A potent but toxic structural analogue of g-aminobutyric acid (GABA), with a zwitterionic structure that can cross the blood-brain barrier.

Biochem/physiol Actions Muscimol hydrobromide is a GABAA receptor agonist.

References 1) Akhondzadeh et al. (1995), Induction of a novel form of hippocampal long-term depression by muscimol: involvement of GABAA but not glutamate receptors; Br. J. Pharmacol., 115 527