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Postion:Product Catalog >API>Antipyretic analgesics>Nonsteroidal Anti-Inflammatory Drugs (NSAIDS)> Naproxen Sodium
 Naproxen Sodium
  •  Naproxen Sodium
  •  Naproxen Sodium
  •  Naproxen Sodium
  •  Naproxen Sodium
  •  Naproxen Sodium

Naproxen Sodium NEW

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 1000kg
Update Time: 2024-04-07

Product Details

Product Name: Naproxen Sodium CAS No.: 26159-34-2
EC-No.: 247-486-2 Min. Order: 1kg
Purity: 99% Supply Ability: 1000kg
Release date: 2024/04/07

Manufacturer ProvidAPI Anti-Inflammatory Naproxen Sodium Powder Material CAS26159-34-2 Naproxen Sodium


Article illustration

Introduction

1.Product Name:  Naproxen Sodium

2.Other Name:6-methoxy-alpha-methyl-,sodiumsalt,(s)-2-naphthaleneaceticaci;6-methoxy-alpha-methyl-,sodiumsalt,l-(-)-2-naphthaleneaceticaci;

3..CAS NO:26159-34-2

4.Purity: 99%min
5.Appearance:White Powder

6.Molecular formula: C14H13O3.Na

7.Molecular weight:252.24

8.Melting Point :250-251°C

9.Storage:Keep in dark place,Inert atmosphere,Room temperature

Naproxen sodium is a kind of non-steroidal anti-inflammatory analgesic that is easier to be tolerated by humans. It belongs to the phenylpropionic acid compound and exerts anti-inflammatory and analgesic effects by inhibiting the synthesis of prostaglandins.
It is clinically suitable for alleviating various mild to moderate pains, such as pain after tooth extraction and other operations, primary dysmenorrhea and headaches. It is also suitable for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis (Juvenilearthritis), tendinitis, bursitis and acute gouty arthritis. Limits have the effect of relieving symptoms. Psoriatic arthritis and Reiter's syndrome can also be treated with this product. Compared with ibuprofen, fenoprofen, aspirin, sulindac and indomethacin, the effect of symptom relief is similar.
Efficacy and effect
Naproxen sodium has strong anti-inflammatory and analgesic effects, and its main biological effects are:
(1) Inhibit the activity of prostaglandin synthase, thereby reducing capillary permeability;
(2) Reduce the production of superoxide by macrophages to play an anti-inflammatory effect;
(3) Stimulate T inhibitory cell activity;
(4) Reduce pain sensitivity. Compared with ibuprofen, fenoprofen, aspirin, sulindac and indomethacin, the symptom relief effect is similar, but the incidence and severity of adverse reactions in the gastrointestinal tract and nervous system are lower.

ItemsStandardTest Result
AppearanceWhite or almost white crystalline powderWhite crystalline powder
Identification
A. Infrared absorptionThe infrared absorption spectrum is concordant with the reference spectrumConform
B. Ultraviolet AbsorptionAbsorptivities at 272nm, calculated on the dried base, do not differ by more than 3%1%
Specific rotation-17.0°~-15.3°-16.8°
Loss on drying≤1.0%0.2%
Heavy metals≤0.002%<0.002%
Free Naproxen≤1.0%0.1%
Related substances(HPLC)
Impurity D(in-house)≤0.10%<0.01%
Impurity E(in-house, impurity C in EP)≤0.10%<0.01%
Any other impurity≤0.10%<0.01%
Total impurities≤0.5%<0.01%
Residual solvents
Toluene≤50ppm<1ppm
Methanol≤50ppm<4ppm
Assay(on dry basis)98.5%~101.5%100.4%
ConclusionThe results conform with USP38.

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Company Profile Introduction

Shaanxi TNJONE Pharmaceutical Co., Ltd supplies more than 2,000 kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, food additives, natural nutrition ingredients, feed additives, cosmetic additives, intermediates etc. With global sourcing advantages, the group is fully capable of meeting the one-stop sourcing needs of global customers. Today, Shaanxi TNJONE Pharmaceutical Co., Ltd.'s marketing network has spread over more than 100 countries and regions on five continents, providing professional service for global customers.

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Shaanxi TNJONE Pharmaceutical Co., Ltd

1YR ChinaChina
  • Since: 2019-05-23
  • Address: No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New C
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