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Postion:Product Catalog >Biochemical Engineering>Enzymes And Coenzymes drugs>NMN Nicotinamide mononucleotide
NMN Nicotinamide mononucleotide
  • NMN Nicotinamide mononucleotide

NMN Nicotinamide mononucleotide

Price Get Latest Price
Package 1KG
Min. Order: 1KG
Supply Ability: 100TONS
Update Time: 2023-04-10

Product Details

Product Name: NMN Nicotinamide mononucleotide CAS No.: 1094-61-7
EC-No.: 214-136-5 Min. Order: 1KG
Purity: 99.9% Supply Ability: 100TONS
Release date: 2023/04/10
NMN stands for nicotinamide mononucleotide, a molecule naturally occurring in all life forms. At the molecular level, it is a ribo-nucleotide, which is a basic structural unit of the nucleic acid RNA. Structurally, the molecule is composed of a nicotinamide group, a ribose and a phosphate group. NMN is the direct precursor of the essential molecule nicotinamide adenine dinucleotide (NAD+) and is considered a key component to increase NAD+ levels in cells.


NameNMN Nicotinamide mononucleotide powder 1094-61-7
CAS1094-61-7
EC Number:214-136-5
Purity>99%
Chemical namebeta-Nicotinamide mononucleotide,β-Nicotinamide mononucleotide,beta-NMN,nicotinamide ribonucleotide
Synonymsβ-NMN, Nicotinamide ribotide, Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate, β-Nicotinamide ribose monophosphate, NMN
Molecular FormulaC11H15N2O8P
Molecular Weight334.221 g/mol
InChI KeyDAYLJWODMCOQEW-TURQNECASA-N
FormCrystalline  or Lyophilized white powder
Appearancewhite powder
SolubilitySoluble in water (100 g/l)
ApplicationCosmetic,Supplement,IVD,Pharmaceutical
Testing DocumentAvailable
StabilityStable more than 6 months in room temperature
Bulk Density1.5-7g/ml
Particle size>80 mesh
Storage ConditionKeep dry ,away from light, and store at 2℃- 8℃, long term store at -15℃ to -25℃
Package10gram/bag ,50gram/bag , 1KG/bag, 25KG/drum
λmax210, 265 nm


DESCRIPTION
General description
β-Nicotinamide mononucleotide (β-NMN) is an intermediate in the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed biosynthesis of nicotinamide adenine dinucleotide (NAD+). NAMPT mediates the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to produce β-NMN. β-NMN adenyltransferase subsequently converts β-NMN to NAD+.
Application
β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.
Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD biosynthesis. Instead of the deamidation to nicotinic acid, nicotinamide is directly converted to NMN by nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12). The enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1), which is a member of the nucleotidyltransferase alpha/beta-phosphodiesterase superfamily, catalyzes the reaction NMN + ATP <=> Nicotinamide adenine dinucleotide (NAD) + PPi, representing the final step in the biosynthesis of NAD. NAD is a molecule that plays a fundamental role as a cofactor in cellular redox reactions. Thus NMN is an important metabolite for the maintenance of normal NAD biosynthesis. Circulating NMN levels may play an important role in regulating cell function in physiological and pathophysiological conditions.



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