![N,N-Dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine](/ProductImageEN/2024-07/Large/49b34f8a-718c-420f-8f6f-f3ea402eafaf.png)
![N,N-Dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine](/ProductImageEN/2024-07/Small/49b34f8a-718c-420f-8f6f-f3ea402eafaf.png)
N,N-Dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine
| Price | $3800 |
| Package | 1Kg |
| Min. Order: | 1Kg |
| Supply Ability: | 500 Kg |
| Update Time: | 2024-07-11 |
Product Details
| Product Name: N,N-Dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine | CAS No.: 157488-65-8 |
| Min. Order: 1Kg | Purity: 97 |
| Supply Ability: 500 Kg | Release date: 2024/07/11 |
| N,N-Dimethyldinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine |
(R)-Monophos is an antitumor agent that inhibits the growth of cancer cells. It is a potent inhibitor of DNA synthesis, which is essential for cell division. (R)-Monophos has been shown to be effective against a number of cancer cell lines, including leukemia, lymphoma and breast cancer cells. This drug is synthesized by the cross-coupling reaction between a phosphine and an activated carbonyl group. The mechanism of this reaction involves the formation of an iminium ion intermediate with phosphite as the leaving group. The iminium ion reacts with a chloroformate to produce (R)-monophos and hydrogen chloride as byproducts. Crystal x-ray diffraction data have provided evidence for this mechanism.
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Greetings from R&D Scientific Inc.
We are a leading manufacturer and supplier of wide range of chemical products since 2012.
We offer products from gram to bulk quantity as per the customer's demand. We also accept 30-day payment terms for customer satisfaction. We have experience of shipping products to USA, UK, Germany, Italy.
We have a highly qualified team in Organic synthesis with experience in the area custom synthesis, process development, bulk manufacturing. We deal with the synthesis and supply of the fine chemicals, molecules with best quality.
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Canada- Since: 2021-09-15
- Address: 425 Hespeler Rd, Cambridge, ON, Canada N1R 8J6
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