Product Details
Product Name:
NRX-252114 |
CAS No.:
2763260-39-3 |
Purity:
98.26% |
Supply Ability:
10g |
Release date:
2024/11/16 |
Product Introduction
Bioactivity
名称 | NRX-252114 |
描述 | NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM. |
存储条件 | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (97.98 mM), Sonication is recommended.
|
关键字 | NRX-252114 |
相关产品 | Urea | Wnt pathway activator 1 | Nefopam hydrochloride |
相关库 | 经典已知活性库 | 神经保护化合物库 | 已知活性化合物库 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$1520.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-23 |