Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >NSC 600157
NSC 600157
  • NSC 600157
  • NSC 600157

NSC 600157

Price Get Latest Price
Package 1g 5g 10g
Min. Order: 1g
Supply Ability: 1000
Update Time: 2025-01-11

Product Details

Product Name: NSC 600157 CAS No.: 31083-55-3
Min. Order: 1g Purity: 98
Supply Ability: 1000 Release date: 2025/01/11

Product Name:    NSC 600157

Synonyms:    PRT 4165; PRT-4165; NSC600157; NSC-600157; NSC 600157; 2-(pyridin-3-ylmethylidene)indene-1,3-dione;2-(3-Pyridinylmethylene)-1H-indene-1,3(2H)-dione;2-(3-Pyridylmethylene)-1,3-indandione;NSC 600157;PRT4165;PRT 4165(NSC 600157);1H-Indene-1,3(2H)-dione, 2-(3-pyridinylmethylene)-

CAS:    31083-55-3

MF:    C15H9NO2

MW:    235.24

PRT-4165 (31083-55-3) is an inhibitor of Bmi1/Ring1A, subunits of the polycomb repressive complex 1 (PRC1). Inhibits self-ubiquitination (IC50?= 3.9 μM) but does not increase cellular levels of either subunit. Blocks Bmi1/Ring1A-mediated ubiquitination and drug-induced degradation of topoisomerase 2α.1?PRT-4165 inhibits H2A/H2AX ubiquitination via blocking the E3 ubiquitin ligase activity of RNF2 and a Bmi1/RNF2 complex. Blocks polycomb repressor complex (PRC) 1-mediated histone H2A ubiquitination?in vitro?and?in vivo?and as such represents a new tool for studying chromatin remodeling.2


Company Profile Introduction

Wuhan Circle Star Chem-medical Technology Co.,Ltd is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in electronic chemicals, pharmaceutical intermediates, pesticide intermediates, ultraviolet absorbent, food additives and other fine chemical products research and development, production, sales and operation or agency of various products and technology import and export business. The company has two laboratories (located in wuhan and ningbo), a Chinese workshop (located in wuhan), and two amplification production bases (located in zhejiang and hubei).The company employs a number of postdocs, doctors and professors from wuhan university, huazhong agricultural university, huazhong university of science and technology and other famous universities in China to form the r&d team, and also has its own excellent sales team. The company always adhere to the "technology first, customer first, quality after-sales service" professional philosophy and enterprise spirit.The company can provide excellent products, technical support and perfect after-sales service, and ensure the quality and timely delivery regardless of business size.In order to establish a good reputation among domestic and foreign customers.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$98.00/1mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-19
$1520.00/25mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-23
$242.00/2mg
VIP3Y
TargetMol Chemicals Inc.
2024-10-28
$38.00/5mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-19
$1.00/1KG
VIP6Y
Career Henan Chemical Co
2019-12-23
  • Since: 2024-03-12
  • Address: Room 02-31, 13 / F, Building 9, Guannan Fuxing Medical Park Phase II, No.58, Guanggu Avenue, East La
INQUIRY