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Postion:Product Catalog >Biochemical Engineering>Inhibitors>ODM-201
ODM-201
  • ODM-201
  • ODM-201

ODM-201

Price $40 $38 $35
Package 1Gram 100Gram 10000Gram
Min. Order: 1Gram
Supply Ability: 50Tons
Update Time: 2024-12-12

Product Details

Product Name: ODM-201 CAS No.: 1297538-32-9
Min. Order: 1Gram Purity: 99.99%
Supply Ability: 50Tons Release date: 2024/12/12

ODM-201, also known as Darolutamide, is a new-generation, potent and selective androgen receptor (AR) inhibitor which is potential useful for treatment of castration-resistant prostate cancer (CRPC). ODM-201 is a full and high-affinity AR antagonist that, similar to second-generation antiandrogens enzalutamide and ARN-509. Importantly, ODM-201 also blocks the activity of the tested mutant ARs arising in response to antiandrogen therapies, including the F876L mutation that confers resistance to enzalutamide and ARN-509. In addition, ODM-201 reduces the growth of AR-overexpressing VCaP prostate cancer cells both in vitro and in a castration-resistant VCaP xenograft model. ODM-201 overcomes resistance to AR-targeted therapies by antagonizing both overexpressed and mutated ARs. ODM-201 is currently in a phase 3 trial in CRPC.

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Company Profile Introduction

-.Hebei Dangtong Biological Technology Co.,LTD founded in April 2004,has more than 960employees. Headquartered in Luquan District, Shijiazhuang city,Hebei Province, weare a professional manufacturer of alkaline dyes, chemical raw materials, foodadditives and pharmaceutical intermediates. The company has 3 production bases. Respectively in Hebei, Inner Mongolia, Yunnan three factory bases. It has two research centers and three laboratories specializing in the development of new products and the optimization of existing products. Committed to providing higher quality products and services to meet customer personalized needs. In terms of production, the company insists on integrated production, supplying main raw materials by itself, and laying out lean factories to ensure sustainable and stable supply.

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Hebei Dangtong Import and export Co LTD

3YR ChinaChina
  • Since: 2021-05-08
  • Address: Room 10-0-1001, Chunbei District, Shunde North Road, Xiangdu District, Xingtai city, Hebei Province
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