Omeprazole NEW
| Price | $40 | $48 | $97 |
| Package | 50mg | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Omeprazole | CAS No.: 73590-58-6 |
| Purity: 97.61% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Omeprazole |
| Description | Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). |
| In vitro | Omeprazole transiently alters the kinetic properties of parietal cells in rabbits, leading to premature cell death and expedited growth. By inhibiting H(+)-K(+)-ATPase, omeprazole enhances the clearance of degenerative changes and macrophage-mediated removal of parietal cells, as well as promoting the increase of progenitor cells at the apical ridge. |
| In vivo | Omeprazole diminishes the activation of osteoclasts in vitro, while enhancing the activation of osteoblasts, leading to osteosclerosis-like effects to some extent. In human hepatocellular carcinoma cells, omeprazole induces the transcription of reporter genes through dioxin receptor elements recognized by ligand-activated aryl hydrocarbon receptors. It effectively induces the expression of cytochrome P4501A1 mRNA in primary human hepatocytes, but this induction is not detected in mouse primary hepatocytes. Omeprazole significantly suppresses the basal natural killer (NK) activity in splenocytes (SC) from untreated CD2F1 mice. It exerts rapid and robust effects on various types of cytotoxic lymphocytes, ranging from the inhibition of cytotoxicity to irreversible cellular damage. Furthermore, omeprazole notably inhibits the cytotoxicity of all types of effector cells after 30 minutes of incubation. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | 1eq. HCl : 17.3 mg/mL (50 mM) Ethanol : 20 mg/ml (57.90 mM), Sonication is recommended. DMSO : 100 mg/ml (289.50 mM), Sonication is recommended. |
| Keywords | Omeprazole | inhibit | Inhibitor | Phospholipase | Autophagy | Bacterial | Proton Pump | H-16868 | H16868 |
| Inhibitors Related | Neomycin sulfate | Dimethyl sulfoxide |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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