ONO-AE3-208 NEW
| Price | $58 | $93 | $159 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: ONO-AE3-208 | CAS No.: 402473-54-5 |
| Purity: 98.04% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | ONO-AE3-208 |
| Description | ONO-AE3-208 (AE 3-208) is an EP4 antagonist. It suppresses cell migration, invasion, and metastasis of prostate cancer. |
| In vitro | ONO-AE3-208 abolishes CTGF in the presence of the EET synthesis inhibitor MS-PPOH. Arachidonic acid causes the dose-dependent dilation of the attached Af-Art, and this effect is blocked by ONO-AE3-208 [2]. |
| In vivo | In mice, ONO-AE3-208 significantly reduces bone metastasis of PC3 cells in vivo, as evidenced by reduced photon tumor burdens over time when compared to the control group. Additionally, the rate of metastasis is significantly lower in the ONO-AE3-208-treated group, with a median metastasis formation time of 29 days, compared to 21 days in the control group. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : Insoluble DMSO : 70 mg/mL (173.08 mM), Sonication is recommended. |
| Keywords | ONOAE3208 | ONO AE3 208 | Prostaglandin Receptor | inhibit | ONO-AE-3-208 | Inhibitor | ONO-AE3-208 |
| Inhibitors Related | Angoroside C | Pranoprofen | Tranilast | Benorilate | Rutin | Ozagrel | Ethamsylate | Rebamipide | Evodiamine | Tebufelone | Timapiprant | p-Hydroxycinnamic acid |
| Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Prostate Cancer Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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