PFE-360 NEW
| Price | $68 | $98 | $172 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: PFE-360 | CAS No.: 1527475-61-1 |
| Purity: 99.73% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | PFE-360 |
| Description | PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase, with an in vivo IC50 of 2.3 nM. |
| In vivo | PFE-360 (4 mg/kg and 7.5 mg/kg, orally, BID, 10-12 weeks) treatment effectively reduces the LRRK2-pSer935/total LRRK2 ratio. It has no significant adverse effects[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 3.08 mg/mL (10 mM), Sonication is recommended. |
| Keywords | PF 06685360 | PFE 360 | LRRK2 | inhibit | PFE360 | Inhibitor | Leucine-rich repeat kinase 2 | PFE-360 | PF06685360 |
| Inhibitors Related | GNE0877 | CZC-25146 | GSK2578215A | GNE-9605 | CZC-54252 hydrochloride | GNE-7915 | EB-42486 | LRRK2 inhibitor 1 | LRRK2-IN-7 | LRRK2-IN-1 | CCG-1423 | PF-06454589 |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Kinase Inhibitor Library | Anti-Parkinson's Disease Compound Library | CNS-Penetrant Compound Library | Inhibitor Library | NO PAINS Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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