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Postion:Product Catalog >API>Digestive system drugs>Antacid and Mucosal protective Drugs>POLYDIMETHYLSILOXANE
POLYDIMETHYLSILOXANE
  • POLYDIMETHYLSILOXANE

POLYDIMETHYLSILOXANE NEW

Price $8 $7 $6
Package 1kg 100kg 1000kg
Min. Order: 1kg
Supply Ability: g-kg-tons, sample is available
Update Time: 2024-04-22

Product Details

Product Name: POLYDIMETHYLSILOXANE CAS No.: 8050-81-5
Min. Order: 1kg Purity: 99%
Supply Ability: g-kg-tons, sample is available Release date: 2024/04/22
Lead time: In stock Packaging: bottle/drum/bucket/IBC, as request.
Delivery: By sea, by air, by express Origin: Manufacturer
Contact person: Jessica

1. Product information


Names

NamePOLYDIMETHYLSILOXANE
SynonymMore Synonyms

 Simethicone Biological Activity

DescriptionSimethicone is an orally active defoamer. Simethicone reduces the surface tension of air bubbles in the gastrointestinal tract, causing them to be expelled by vomiting, exhalation or absorption into the bloodstream. Simethicone has potential applications in flatulence and colic[1].
Related Catalog
Research Areas >> Others
Signaling Pathways >> Others >> Others
In Vivo Animal Model: Female adult Wistar rats (200–250 g)[2]. Dosage: 50, 100 and 200 mg/kg. Administration: Oral gavage; single dose. Result: Improved colon permeability and hypersensitivity (200 mg/kg). Animal Model: Adult New Zealand White (NZW) rabbits[3]. Dosage: 20 mg/kg. Administration: Oral gavage; single dose. Result: Improved image quality scores for the jejunum without affecting left kidney, right kidney and gallbladder.
References

[1]. Voepel-Lewis TD, et al. Evaluation of simethicone for the treatment of postoperative abdominal discomfort in infants. J Clin Anesth. 1998 Mar;10(2):91-4.  

[2]. Bueno L, et al. Influence of simethicone and alverine on stress-induced alterations of colonic permeability and sensitivity in rats: beneficial effect of their association. J Pharm Pharmacol. 2013 Apr;65(4):567-73.  

[3]. da Silva KG, et al. Influence of simethicone and fasting on the quality of abdominal ultrasonography in New Zealand White rabbits. Acta Vet Scand. 2017 Jul 17;59(1):48.  

 Chemical & Physical Properties

Density1 g/mL at 20ºC
Boiling Point96.5ºC at 760 mmHg
Molecular FormulaC6H18O4Si3
Molecular Weight238.46100
Flash Point6.3ºC
Exact Mass238.05100
PSA52.60000
LogP1.56770
Appearance of Charactersemulsion | Colorless
Vapour Pressure5 mm Hg ( 20 °C)
Index of Refractionn20/D 1.406
Storage conditionroom temp
Water SolubilityPractically insoluble in water, very slightly soluble or practically insoluble in anhydrous ethanol, practically insoluble in methanol, partly miscible with ethyl acetate, with methylene chloride, with methyl ethyl ketone and with toluene.



2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 

Article illustrationArticle illustration

3. Shipping

Article illustration


4. Contact information

For more details, pls contact us freely.

Mob: 86 17630971917

WhatsApp/Skype/Wechat/LINE: 86 17630978909


Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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Career Henan Chemical Co
2019-12-30
  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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