Promethazine hydrochloride NEW
| Price | Get Latest Price | ||
| Package | 100g | 500g | 1000g |
| Min. Order: | 100g |
| Supply Ability: | 20 tons |
| Update Time: | 2023-09-14 |
Product Details
| Product Name: Promethazine hydrochloride | CAS No.: 58-33-3 |
| EC-No.: 200-375-2 | Min. Order: 100g |
| Purity: 99% | Supply Ability: 20 tons |
| Release date: 2023/09/14 |
Contact me: admin06@hsnm.com.cn
Product Description
| Product Name: | Promethazine hydrochloride |
| CAS: | 58-33-3 |
| MF: | C17H21ClN2S |
| MW: | 320.88 |
| EINECS: | 200-375-2 |
| Melting point | 230-232°C |
| Fp | 9ºC |
| storage temp. | 2-8°C |
| solubility | Very soluble in water, freely soluble in ethanol (96 per cent) and in methy lene chloride. |
| form | neat |
| color | White to Almost white |
| PH | pH (50g/L, 25ºC) : 4.0~6.0 |
| λmax | 297nm(H2O)(lit.) |
| Merck | 14,7786 |
| BRN | 4166397 |
Antihistaminic, antiemetic, CNS depressant
stool softener
For the treatment of allergic disorders, and nausea/vomiting.
Promethazine is a first generation histamine H1 receptor antagonist (Ki = 2.6 nM) whose antihistamine activity has been reported in guinea pigs and mice at ED50 values of 0.43 and 5.9 mg/kg, respectively. Promethazine can penetrate the CNS, depressing central H1 receptor activity, which may relate to its sedative properties, and can also inhibit muscarinic acetylcholine receptors (Ki = 22 nM). Furthermore, 32 mg/kg promethazine demonstrates antiemetic effects in ferret models of motion sickness or chemotherapy-induced nausea.
Promethazine hydrochloride is used as antihistamine; antiemetic; central nervous system depressant; sedative; anticholinergic; antiserotoninergic; local anesthetic; in the treatment of motion sickness, cough linctuses, nausea, and allergic conditions; used to control Parkinsonian symptoms and as central nervous system depressant; in pills, syrup, injections and suppositories.
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My email: admin06@hsnm.com.cn
Company Profile Introduction
Wuhan Hansheng New Material Technology Co.Ltd founded in 2022.
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Our company is a professional manufacturer leading factory in China in pharmaceutical area for many years, our products have exported to USA,Greece, Spain, UK, Germany, Australia and other countries, and we have got very good feedback from our customers, we had established a long term friendly relations with our customers all over the world, and in some area like Europe and North America,
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China- Since: 2022-09-29
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