Product Details
| Product Name:
PU23 |
CAS No.:
817635-93-1 |
| Purity:
98.33% |
Supply Ability:
10g |
| Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | PU23 |
| Description | PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4). |
| In vitro | 6-Mercaptopurine (6-MP) inhibits HEK293 and HEK293/MRP4 cells with IC50s of 2.81 and 14.11 μM, respectively. Combined with PU23, 6-MP inhibits these cells with IC50s of 1.84 and 6.06 μM. Preincubation of HEK293/MRP4 cells with PU 23 (50 μM) for 2 hours significantly increases the intracellular concentration of 6-MP [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 55 mg/mL (129.25 mM)
|
| Keywords | MRP4 | PU23 | resistance | Inhibitor | inhibit | protein | 6-Mercaptopurine | PU-23 | multidrug | PU 23 |
| Inhibitors Related | Fluoxetine | Cyclophosphamide hydrate | Prazosin hydrochloride | 3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide | Perindopril erbumine | Cholesterol | Estriol | Benzocaine | Flurbiprofen | Cyclophosphamide | Clarithromycin | Ketoprofen |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States