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Postion:Product Catalog >API>RAD140
RAD140
  • RAD140
  • RAD140
  • RAD140
  • RAD140

RAD140 NEW

Price $15
Package 1KG
Min. Order: 1KG
Supply Ability: large quantity
Update Time: 2024-01-18

Product Details

Product Name: RAD140 CAS No.: 1182367-47-0
Min. Order: 1KG Purity: 99%
Supply Ability: large quantity Release date: 2024/01/18

WhatsApp:+8613043004613

Telegram: @Sara2215

Email: Sara@xmwonderfulbio.com

Payment: Bitcoin, Western Union, T/T, Moneygram, paypal for your choices



Common NameRAD140
CAS Number1182367-47-0Molecular Weight393.826
Density1.4±0.1 g/cm3Boiling Point687.7±65.0 °C at 760 mmHg
Molecular FormulaC20H16ClN5O2Melting PointN/A
MSDSN/AFlash Point369.7±34.3 °C





Use of RAD140


RAD140 is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). IC50 value: 7 nM (Ki, fot androgen receptor) [1]Target: androgen receptor in vitro: RAD140 demonstrates excellent affinity for the androgen receptor (Ki = 7 nM) as well as good selectivity over other steroid hormone nuclear receptors, with the closest off target receptor being the progesterone receptor (IC50 = 750 nM). [1] RAD140 is a novel SARM with high affinity and specificity for AR, is orally available, and exhibits potent anabolic effects in rodents and nonhuman primates.[2]in vivo: The stability of RAD140 is high (t1/2 > 2 h) in incubations with rat, monkey, and human microsomes, and it also had good bioavailability in rats and monkeys. [1] RAD140 is also neuroprotective using the rat kainate lesion model. RAD140 is shown to exhibit peripheral tissue-specific androgen action that largely spared prostate, neural efficacy by activation of androgenic gene regulation effects, and neuroprotection of hippocampal neurons against cell death caused by systemic administration of the excitotoxin kainate.[2]





Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point687.7±65.0 °C at 760 mmHg
Molecular FormulaC20H16ClN5O2
Molecular Weight393.826
Flash Point369.7±34.3 °C
Exact Mass393.099243
PSA118.76000
LogP3.02
Vapour Pressure0.0±2.3 mmHg at 25°C
Index of Refraction1.652





Synonyms

2-Chloro-4-({(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl}amino)-3-methylbenzonitrile
rad140
Benzonitrile, 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methyl-
RAD-140





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FAQ:

 

1: Can I have a sample order for your products?

 

Yes, we can supply the free sample, but the shipping cost be paid by our customers.

 

 

2: How to confirm the Product Quality before placing orders?

 

1) You can get free samples for some products, just pay the basic cost for us.

2) Also you can send the specification or your request to us, we will customize the products for you.

 

 

3: How do you deal with quality complaints?

 

A: first of all, our quality control will reduce the quality problem to nearly zero. If the actual quality problem is caused by us, we will send you free goods for replacement or refund.

 

 

4: Can you give me a discount?

 

A: Of course, it depends on your quantity.

 

 

5:Are you a trading company or a manufacturer?

 

We are both, so we can always provide wholesale price and most products in stock.

 

 

6:How to contact us?

 

You can chat with us by Whatsapp ,Telegram,& Wickr me Online.

You can choose your interested products and send inquiry to us.

You can send Email to us, you will get our reply.

 

 

7: Which kind of payment do you accept?

 

 T/T,Paypal,Visa,L/C,Western Union,or according to your needs.

 

 

8: Package

 

We have standard package, or it can be customized as per your request.

 

 

9: Transportation

 

UPS,TNT,EMS,Fedex,and so on.According to your location, safe customs clearance, generally delivered to your door within7 -15 days in Europe and the United States.

 








Company Profile Introduction

Xiamen Wonderful Bio Technology Co., Ltd. is a professional company engaged in pharmaceutical and chemical engineering, raw materials, and plant extracts. Our company has long-term cooperation with multiple universities such as the Fujian Academy of Research and the Academy of Medical Sciences. Our company integrates research and development, production, and sales, and has advanced research and development equipment with strong technology. Our company also supports customization of some special products. Our company provides high-quality chemical raw materials, pharmaceutical intermediates, and industrial chemicals to the world. Our products are exported to over 70 countries overseas. Strict quality management system and comprehensive after-sales service. Everything is based on customer satisfaction, and everything is based on the long-term healthy development of the enterprise.

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  • Since: 2023-02-16
  • Address: Room 727, No. 600-3 Nanhai 3rd Road, Xiamen Section, China (Fujian) Pilot Free Trade Zone
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