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Postion:Product Catalog >API>Digestive system drugs>Gastric Acid Inhibitors>Ratic
Ratic
  • Ratic
  • Ratic
  • Ratic

Ratic

Price $280
Package 1KG
Min. Order: 1KG
Supply Ability: Ex 20 tons
Update Time: 2022-09-16

Product Details

Product Name: Ratic CAS No.: 66357-35-5
EC-No.: 266-332-5 Min. Order: 1KG
Purity: 99% Supply Ability: Ex 20 tons
Release date: 2022/09/16

Ratic Biological Activity

DescriptionRanitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. Ranitidine is a weak inhibitor of CYP2C19 and CYP2C9[1][2].
Related Catalog
Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor
Research Areas >> Endocrinology
Research Areas >> Infection
Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
Research Areas >> Metabolic Disease
Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Signaling Pathways >> Anti-infection >> Bacterial
Target

H2 Receptor:3.3 μM (IC50)

CYP2C19

CYP2C9

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

ShippingRoom temperature
SMILESO=[N+](/C=C(NC)/NCCSCC1=CC=C(CN(C)C)O1)[O-]
References

[1]. A W Herling, et al. Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460). Agents Actions. 1987 Feb;20(1-2):35-9.

[2]. A Leucuta, et al. A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact. 2004;20(4):273-81.

[3]. Antonio Francesco Ciccaglione, et al. Pylera® plus ranitidine vs Pylera® plus esomeprazole in first-line treatment of Helicobacter pylori infection: Two pilot studies. Helicobacter. 2019 Oct;24(5):e12606.



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  • Since: 2022-02-24
  • Address: 3-1-1005, Federal Business Plaza, 166 Yuhua West Road, Qiaoxi District, Shijiazhuang City, Hebei Pro
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