Retatrutide
Price | Get Latest Price | ||
Package | 1kg | 25kg | 50kg |
Min. Order: | 1kg |
Supply Ability: | 50tons |
Update Time: | 2023-09-14 |
Product Details
Product Name: Retatrutide | CAS No.: 2381089-83-2 |
EC-No.: 200-001-8 | Min. Order: 1kg |
Purity: 99% | Supply Ability: 50tons |
Release date: 2023/09/14 |
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What are the specifications of this product?
Product Name: | Retatrutide |
CAS: | 2381089-83-2 |
EINECS: | 200-001-8 |
storage temp. | -20°C |
form | powder |
color | White lyophilized |
Water Solubility | Soluble in water (5mg/ml). |
Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insu-linotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.
Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insu-lin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.
Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating in-sulin and suppressing glucagon secretion in a glucose-dependent manner.
Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
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