RIPK1-IN-7 NEW
| Price | $93 | $228 | $347 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: RIPK1-IN-7 | CAS No.: 2300982-44-7 |
| Purity: 98.02% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | RIPK1-IN-7 |
| Description | RIPK1-IN-7 is a potent and selective inhibitor of RIPK1 (Kd of 4 nM and enzymatic IC50 of 11 nM), exhibiting excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model. |
| In vitro | In the TSZ-induced HT29 cell necroptosis model, RIPK1-IN-7 shows potent cell protection effect (EC50 of 2nM). RIPK1-IN-7 displays considerable activity against several other kinases(Flt4, TrkA, TrkB, TrkC, Axl, HRI, Mer, and MAP4K5 with IC50s of 20, 26, 8, 7, 35, 26, 29, and 27 nM, respectively). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 60 mg/mL (124.62 mM), Sonication is recommended. H2O : 0.1 mg/mL (insoluble) |
| Keywords | TrkC | TrkB | TrkA | RIPK1-IN-7 | RIPK-1-IN-7 | RIPK1IN7 | RIPK1 IN 7 | RIPK | RIP kinase | Receptor-interacting protein kinases | Mer | Inhibitor | inhibit | HRI | Flt4 | Axl |
| Inhibitors Related | PK68 | Necrostatin-1 | RIPK2-IN-5 | Oditrasertib | LY-364947 | Necroptosis-IN-1 | ICCB-19 hydrochloride | RIPK1-IN-9 | Necrostatin-34 | RIPA-56 | GSK2983559 free acid | Zharp2-1 |
| Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Breast Cancer Compound Library | Anti-Ovarian Cancer Compound Library | Inhibitor Library | NO PAINS Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Liver Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hills
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